ReviewFrontiers in plant science2015
To die or not to die? Lessons from lesion mimic mutants.
Review in Frontiers in plant science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 97 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
97 citing papers in PubMed, 194 citations in OpenAlex.
- A conserved phospho-switch controls receptor kinase SDS2 activation and homeostasis in rice immunity.Science advances · 2026Article
- Impairment of the Uroporphyrinogen Decarboxylase 2 Gene Induces Lesion Mimicry and Downregulates Tetrapyrrole Biosynthesis Pathway Genes in Rice.Rice (New York, N.Y.) · 2026Article
- Coordinated single-nucleus responses for quantitative disease resistance involve a calcium-associated switch in transcriptional noise.Genome biology · 2025Article
- Genome-wide dissection of lesion mimic mutations in wheat: identification and functional characterization of candidate genes.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Different Light Wavelengths Differentially Influence the Progression of the Hypersensitive Response Induced by Pathogen Infection in Tobacco.Antioxidants (Basel, Switzerland) · 2025Article
- The Histidine-25-Arginine Mutation in the Rice MACPF Protein OsCAD1 Induces Cell Death and Activates Defense Responses in the Lesion Mimic Mutant spl17.Rice (New York, N.Y.) · 2025Article
- Durum wheat mutants with enhanced disease resistance to stripe rust show differential responses to other fungal diseases.Molecular breeding : new strategies in plant improvement · 2025Article
- Integrated Transcriptomic and Metabolomic Analyses Reveal the Importance of the Terpenoid, Fatty Acid, and Flavonoid Pathways in Rice Cell Death and Defense.Plants (Basel, Switzerland) · 2025Article
- Stress sensing and response through biomolecular condensates in plants.Plant communications · 2025Review
- Altering cold-regulated gene expression decouples the salicylic acid-growth trade-off in Arabidopsis.The Plant cell · 2024Article
- Roles of microbiota in autoimmunity in Arabidopsis leaves.Nature plants · 2024Article
- Genome-wide identification of Ankyrin (ANK) repeat gene families in three Dendrobium species and the expression of ANK genes in D. officinale under gibberellin and abscisic acid treatments.BMC plant biology · 2024Article
- Revisiting growth-defence trade-offs and breeding strategies in crops.Plant biotechnology journal · 2024Review
- Type II metacaspase mediates light-dependent programmed cell death in Chlamydomonas reinhardtii.Plant physiology · 2024Article
- A single amino acid substitution in the AAA-type ATPase LRD6-6 activates immune responses but decreases grain quality in rice.Frontiers in plant science · 2024Article
- Genetic characterization and linkage analysis of spotted leaf 6,liguleless and lax panicle traits in mutant rice.Journal of genetics · 2024Article
- Rising from the dead: the power of genome editing.Science China. Life sciences · 2023Article
- TaRBP1 stabilizes TaGLTP and negatively regulates stripe rust resistance in wheat.Molecular plant pathology · 2023Article
- OsMKK6 Regulates Disease Resistance in Rice.International journal of molecular sciences · 2023Article
- Salicylic acid metabolism and signalling coordinate senescence initiation in aspen in nature.Nature communications · 2023Article
37 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Programmed cell death (PCD) is a ubiquitous genetically regulated process consisting in an activation of finely controlled signaling pathways that lead to cellular suicide. Although some aspects of PCD control appear evolutionary conserved between plants, animals and fungi, the extent of conservation remains controversial. Over the last decades, identification and characterization of several lesion mimic mutants (LMM) has been a powerful tool in the quest to unravel PCD pathways in plants. Thanks to progress in molecular genetics, mutations causing the phenotype of a large number of LMM and their related suppressors were mapped, and the identification of the mutated genes shed light on major pathways in the onset of plant PCD such as (i) the involvements of chloroplasts and light energy, (ii) the roles of sphingolipids and fatty acids, (iii) a signal perception at the plasma membrane that requires efficient membrane trafficking, (iv) secondary messengers such as ion fluxes and ROS and (v) the control of gene expression as the last integrator of the signaling pathways.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.