ArticleBrain : a journal of neurology2015
Cerebrospinal fluid leakage and headache after lumbar puncture: a prospective non-invasive imaging study.
Article in Brain : a journal of neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Peripheral Nerve Blocks for Postdural Puncture Headache: A New Solution for an Old Problem?In vivo (Athens, Greece)Pooled it
- Elevated Plasma microRNA-206 Levels Predict Cognitive Decline and Progression to Dementia from Mild Cognitive Impairment.Biomolecules · 2019Trial
- Optimal management after paediatric lumbar puncture: a randomized controlled trial.BMC neurology · 2019Trial
- Investigation of the optimal duration of bed rest in the supine position to reduce complications after lumbar puncture combined with intrathecal chemotherapy: a multicenter prospective randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018Trial
- Pulsatile Tinnitus as the Primary Symptom in IIH: A Distinct Clinical Entity.The Laryngoscope · 2025Article
- Herniation secondary to critical cerebrospinal fluid hypovolemia after supratentorial craniotomy: a single-center case series.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Deep learning-based reconstruction for 3-dimensional heavily T2-weighted fat-saturated magnetic resonance (MR) myelography in epidural fluid detection: image quality and diagnostic performance.Quantitative imaging in medicine and surgery · 2024Article
- Comparing 2-dimensional versus 3-dimensional MR myelography for cerebrospinal fluid leak detection.European journal of radiology open · 2024Article
- Research productivity on spontaneous intracranial hypotension: A bibliometric analysis.Brain & spine · 2024Article
- Paravertebral Cerebrospinal Fluid Exudation in Young Women with Postdural Puncture Headache: A Hypothetical Interpretation based on Anatomical Study on Intervertebral Foramen.Asian journal of neurosurgery · 2023Article
- Iatrogenic CSF Leak from CT Myelogram Leading to Cauda Equina Compression: A Case Report.Journal of orthopaedic case reports · 2022Article
- Case of extensive cerebrospinal fluid leak postlumbar puncture in a paediatric patient with idiopathic intracranial hypertension.BMJ case reports · 2022Article
- Treatment, Outcome, and Relapse of Spontaneous and Nonspontaneous Cerebrospinal Fluid Leak.Brain sciences · 2022Article
- Erythrocyte sphingolipid species as biomarkers of Alzheimer's disease.Journal of pharmaceutical analysis · 2022Article
- Recent Advances in Understanding of Alzheimer's Disease Progression through Mass Spectrometry-Based Metabolomics.Phenomics (Cham, Switzerland) · 2022Article
- Magnetic resonance imaging predicted the therapeutic response of patients with spinal cerebrospinal fluid leakage undergoing targeted epidural blood patch.The British journal of radiology · 2022Article
- Risk factors for nonresponsive hydration in patients with spinal cerebrospinal fluid leakage.BMC neurology · 2021Article
- The causal-effect of bed rest and post-dural puncture headache in patients receiving diagnostic lumbar puncture: A prospective cohort study.Journal of the Chinese Medical Association : JCMA · 2021Article
- Delayed diagnosis of bilateral subdural effusions complicating intracranial hypotension in a patient presenting with post lumbar puncture headache.BMJ case reports · 2021Article
- Differential effects on blood and cerebrospinal fluid immune protein markers and kynurenine pathway metabolites from aerobic physical exercise in healthy subjects.Scientific reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The spatial distribution and clinical correlation of cerebrospinal fluid leakage after lumbar puncture have not been determined. Adult in-patients receiving diagnostic lumbar punctures were recruited prospectively. Whole-spine heavily T2-weighted magnetic resonance myelography was carried out to characterize post-lumbar puncture spinal cerebrospinal fluid leakages. Maximum rostral migration was defined as the distance between the most rostral spinal segment with cerebrospinal fluid leakage and the level of lumbar puncture. Eighty patients (51 female/29 male, mean age 49.4 ± 13.3 years) completed the study, including 23 (28.8%) with post-dural puncture headache. Overall, 63.6% of periradicular leaks and 46.9% of epidural collections were within three vertebral segments of the level of lumbar puncture (T12-S1). Post-dural puncture headache was associated with more extensive and more rostral distributions of periradicular leaks (length 3.0 ± 2.5 versus 0.9 ± 1.9 segments, P = 0.001; maximum rostral migration 4.3 ± 4.7 versus 0.8 ± 1.7 segments, P = 0.002) and epidural collections (length 5.3 ± 6.1 versus 1.0 ± 2.1 segments, P = 0.003; maximum rostral migration 4.7 ± 6.7 versus 0.9 ± 2.4 segments, P = 0.015). In conclusion, post-dural puncture headache was associated with more extensive and more rostral distributions of periradicular leaks and epidural collections. Further, visualization of periradicular leaks was not restricted to the level of dural defect, although two-thirds remained within the neighbouring segments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.