ArticleBMJ case reports2015
An unusual association of Ménétrier's disease with a gastric bezoar.
Article in BMJ case reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 6 citations in OpenAlex.
- Menetrier disease and Cytomegalovirus infection in paediatric age: report of three cases and a review of the literature.European journal of pediatrics · 2021Review
- Diagnosis and Management of Ménétrier Disease in Children: A Case Series Review.Pediatric gastroenterology, hepatology & nutrition · 2021Article
- Upper Gastrointestinal Manifestation of Bezoars and the Etiological Factors: A Literature Review.Gastroenterology research and practice · 2019Review
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Authors and funding
3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Ménétrier's disease is a rare protein-losing hypertrophic gastroenteropathy. While it still remains a medical curiosity, infection with Cytomegalovirus and Helicobacter pylori, and hormonal, congenital, dietary and neurogenic factors have been postulated as causative factors. We describe a case of a 14-year boy who presented with epigastric discomfort, vomiting, inability to gain weight and pedal oedema. Investigations revealed hypoproteinaemia without proteinuria and elevated faecal α-1-antitrypsin levels suggestive of protein-losing enteropathy. Imaging and endoscopic features demonstrated cerebriform gastric folds indicative of Ménétrier's disease. Infective, hormonal and neurogenic causes were ruled out in our patient. Surprisingly, the patient had a history of pica and an associated large gastric bezoar, which was ultimately removed surgically. An association of Ménétrier's disease with a bezoar has been reported only once previously. We thus add to the existing literature and highlight the plausible role of a bezoar as a causative factor in the pathogenesis of Ménétrier's disease due to its irritant nature.
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