ArticleOphthalmology2015
Sarcoidosis in the national veteran population: association of ocular inflammation and mortality.
Article in Ophthalmology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Diagnosis and Detection of Sarcoidosis. An Official American Thoracic Society Clinical Practice Guideline.American journal of respiratory and critical care medicine · 2020Guideline
- Genomic network analysis links uveitis with systemic inflammatory diseases.medRxiv : the preprint server for health sciences · 2026Article
- Sarcoid Uveitis with Choroidal Involvement.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Risk factors for uveitis in a Finnish sarcoid population.Acta ophthalmologica · 2025Article
- Epidemiology, clinical features, and classification of 3,404 patients with uveitis: Colombian Uveitis Multicenter Study (COL-UVEA).Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Ocular sarcoidosis, to screen or not to screen?Frontiers in medicine · 2024Review
- The large Hellenic Study of Uveitis: epidemiology, etiologic factors and classification.International ophthalmology · 2023Observational
- Sarcoidosis-Related Uveitis: A Review.Journal of clinical medicine · 2023Review
- Progress in the diagnosis of ocular sarcoidosis.Indian journal of ophthalmology · 2022Review
- The impact of demographic disparities in the presentation of sarcoidosis: A multicenter prospective study.Respiratory medicine · 2021Article
- Extrapulmonary sarcoidosis with a focus on cardiac, nervous system, and ocular involvement.EClinicalMedicine · 2021Review
- Review
- Uveitis as an Open Window to Systemic Inflammatory Diseases.Journal of clinical medicine · 2021Article
- Ocular sarcoidosis: clinical experience and recent pathogenetic and therapeutic advancements.International ophthalmology · 2020Article
- Clinical Characteristics of Sarcoidosis in Asian Population: A 14-year Single Center Retrospective Cohort Study from Thailand.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2020Article
- Ocular Manifestations of Sarcoidosis in a South Florida Population.Clinical ophthalmology (Auckland, N.Z.) · 2020Article
- Clinical Manifestations, Diagnosis, and Treatment of Sarcoidosis.Mayo Clinic proceedings. Innovations, quality & outcomes · 2019Review
- Macular edema associated with non-infectious uveitis: pathophysiology, etiology, prevalence, impact and management challenges.Clinical ophthalmology (Auckland, N.Z.) · 2019Review
- Clinical Characteristics of Ocular Sarcoidosis: A Population-Based Study 1976-2013.Ocular immunology and inflammation · 2019Article
- Noninfectious uveitis in the Asia-Pacific region.Eye (London, England) · 2019Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
purposeTo describe the distribution of ocular sarcoidosis in the veteran population and to determine the association between ocular disease and all-cause mortality.
designRetrospective review.
methodsThe Veterans Health Administration National Patient Care Database information on medical diagnoses, date of diagnosis, age, race, gender, and Veterans Administration medical center station number for site-specific calculations for fiscal years 2010 through 2012 was collected. Mortality data were obtained from the Beneficiary Identification Records Locator Subsystem. The patient cohort was identified with a primary diagnosis of sarcoidosis using International Classification of Disease, ninth edition, code of 135 in outpatient treatment files for the study period. The sarcoidosis patients were divided into those with uveitis or orbital inflammation (defined as ocular inflammation for this study) and those without uveitis or orbital inflammation. Survival analysis was performed using the Cox proportional hazard method.
main outcome measureAssociation between ocular inflammation and 1-year mortality.
resultsOf 15 130 subjects with sarcoidosis, 3364 (22.2%) were evaluated in an eye clinic within a Veterans Administration Medical Center. Most patients were diagnosed with anterior uveitis (n = 1013; 80.7% of ocular inflammation), and the least common diagnosis was orbital granuloma (n = 28; 2.2% of ocular inflammation). Male gender was protective to the development of uveitis (estimate, 0.76; 95% confidence interval, 0.65-0.88; P = 0.0005). The overall 1-year all-cause mortality for all patients with a diagnosis of sarcoidosis was 2.0%. Ocular inflammation was associated with a decrease in 1-year all-cause mortality (simple model: hazard ratio, 0.36; P = 0.0015; complex model: hazard ratio, 0.35; P = 0.013).
conclusionsVeterans with ocular inflammation had significantly lower 1-year all-cause mortality than those without documented ocular inflammation. The reason for this finding remains to be established.
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