Evidence map›Paper›PMID 25687003›Full record

ArticleMaterials science & engineering. C, Materials for biological applications2015

Titania nanotube arrays as interfaces for neural prostheses.

Jonathan A Sorkin, Stephen Hughes, Paulo Soares, Ketul C Popat

Open access · greenAbstract read
In one paragraph

Article in Materials science & engineering. C, Materials for biological applications, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Improved hemocompatibility and reduced bacterial adhesion on superhydrophobic titania nanoflower surfaces.Materials science & engineering. C, Materials for biological applications · 2021
    Article
  7. Crystallinity of TiOJournal of materials science. Materials in medicine · 2020
    Article
  8. Interaction of blood plasma proteins with superhemophobic titania nanotube surfaces.Nanomedicine : nanotechnology, biology, and medicine · 2019
    Article
  9. Article
  10. Antibacterial activity on superhydrophobic titania nanotube arrays.Colloids and surfaces. B, Biointerfaces · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Jonathan A SorkinDepartment of Mechanical Engineering, Colorado State University, Fort Collins CO 80523, USA.
Stephen HughesDepartment of Chemical and Biological Engineering, Colorado State University, Fort Collins CO 80523, USA; School of Biomedical Engineering, Colorado State University, Fort Collins CO 80523, USA.
Paulo SoaresDepartment of Mechanical Engineering, Polytechnic School, Pontifícia Universidade Católica do Paraná, Curitiba, PR 80215-901, Brazil.
Ketul C PopatDepartment of Mechanical Engineering, Colorado State University, Fort Collins CO 80523, USA; School of Biomedical Engineering, Colorado State University, Fort Collins CO 80523, USA. Electronic address: ketul.popat@colostate.edu.
Colorado State University · USPontifícia Universidade Católica do Paraná · BR

Funding

Nanoscale Polymeric Templates for Orthopedic Tissue EngineeringR21AR057341 · NIAMS · COLORADO STATE UNIVERSITY · PI POPAT, KETUL CHANDRAKANT · 2010 to 2011
$324k
NIAMS NIH HHS 5-R21-AR057341-02NIAMS NIH HHS R21 AR057341
6 · The paper itself

Abstract

Neural prostheses have become ever more acceptable treatments for many different types of neurological damage and disease. Here we investigate the use of two different morphologies of titania nanotube arrays as interfaces to advance the longevity and effectiveness of these prostheses. The nanotube arrays were characterized for their nanotopography, crystallinity, conductivity, wettability, surface mechanical properties and adsorption of key proteins: fibrinogen, albumin and laminin. The loosely packed nanotube arrays fabricated using a diethylene glycol based electrolyte, contained a higher presence of the anatase crystal phase and were subsequently more conductive. These arrays yielded surfaces with higher wettability and lower modulus than the densely packed nanotube arrays fabricated using water based electrolyte. Further the adhesion, proliferation and differentiation of the C17.2 neural stem cell line was investigated on the nanotube arrays. The proliferation ratio of the cells as well as the level of neuronal differentiation was seen to increase on the loosely packed arrays. The results indicate that loosely packed nanotube arrays similar to the ones produced here with a DEG based electrolyte, may provide a favorable template for growth and maintenance of C17.2 neural stem cell line.

Indexed as

AdsorptionAnimalsCell AdhesionCell DifferentiationCell LineCells, CulturedLamininMiceNanotubesNeural ProsthesesNeural Stem CellsProstheses and ImplantsSurface PropertiesTitaniumWettabilityLamininTitaniumtitanium dioxideAstrocytesC17.2 neural stem cell lineNeural prosthesesNeuronsTitania nanotube arrays

Identifiers

PMID25687003
PMCPMC4331648
OpenAlexW2072458930

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.