Evidence map›Paper›PMID 25686799›Full record

ReviewPharmacoEconomics2015

The Challenges and Opportunities Associated with Reimbursement for Obesity Pharmacotherapy in the USA.

Charles Baum, Katherine Andino, Eric Wittbrodt, Shelley Stewart, Keith Szymanski, Robin Turpin

Abstract readReview
In one paragraph

Review in PharmacoEconomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Trial
  2. Article
  3. The 'Obesity First' approach: Redefining the future of healthcare.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Review
  4. Barriers and enablers to effective weight management for people living with overweight and obesity: A rapid scoping review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Breaking down silos: the multifaceted nature of obesity and the future of weight management.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  12. The Relative Value of Anti-Obesity Medications Compared to Similar Therapies.ClinicoEconomics and outcomes research : CEOR · 2023
    Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Semaglutide: Charting New Horizons in GLP-1 Analogue Outcome Studies.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2020
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Charles BaumU.S. Medical Affairs, Takeda Pharmaceuticals U.S.A., One Takeda Parkway, Deerfield, IL, 60015, USA, charles.baum@takeda.com.
Katherine Andino
Eric Wittbrodt
Shelley Stewart
Keith Szymanski
Robin Turpin

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity has become a serious public health problem that has stimulated primordial and primary prevention efforts, and a triad of management options (lifestyle, pharmacotherapy, and surgical interventions). A growing body of evidence supports the need for a multi-pronged, clinic-based approach that leverages the synergy between pharmaceutical and lifestyle modification. Recent US policy changes-namely, the passage of the Patient Protection and Affordable Care Act coupled with recognition of obesity as a disease by the American Medical Association-suggest that financial incentives and attitudes towards obesity management are changing. This paradigm shift has implications for current and future obesity pharmacotherapy. However, barriers to pharmacotherapy utilization include patient and physician perceptions of modest efficacy, historical safety issues, regulatory obstacles, and lack of reimbursement. The shifting attitudes and challenges associated not only with a multi-payer system, but also the lack of clearly defined cross-payer reimbursement strategies, prompted a survey to determine coverage for obesity treatment. Participants indicated that federal/state mandates and growth of quality-driven healthcare initiatives will eventually drive wider pharmacotherapy reimbursement within 1-5 years. There are signs that federal/state programs are already moving towards reimbursement by improving quality measures to track obesity outcomes and reduce costs. Future research on clinical and economic outcomes of combination weight-management programs coupled with innovative approaches (e.g., eHealth) in the real-world setting that demonstrate value to patients, healthcare providers, payers, and employers will help reshape obesity management by reducing barriers and broadening reimbursement coverage for anti-obesity pharmacotherapy.

Indexed as

Anti-Obesity AgentsHumansInsurance, Health, ReimbursementLife StyleObesityUnited StatesAnti-Obesity Agents

Identifiers

PMID25686799
PMCPMC4486408

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.