Evidence map›Paper›PMID 25686595›Full record

ArticleClinical research in cardiology supplements2015

Indications for apheresis as an ultima ratio treatment of refractory hyperlipidemias.

P Grützmacher, C Kleinert, C Dorbath, B Öhm

Open access · hybridAbstract read
In one paragraph

Article in Clinical research in cardiology supplements, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

P GrützmacherMedizinische Klinik II, AGAPLESION Markus Krankenhaus Nephrologie, Hochdruck- und Gefäßkrankheiten, Wilhelm-Epstein-Straße 4, 60431, Frankfurt am Main, Germany, Peter.Gruetzmacher@fdk.info.
C Kleinert
C Dorbath
B Öhm
Agaplesion Frankfurter Diakonie Kliniken · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipid apheresis is at present well established in routine treatment of diverse hyperlipoproteinemias refractory to conventional dietary and medical regimens, especially in countries with high medical and socioeconomic standards. Severe familial hypercholesterolemia with atherosclerotic vessel disease involving the coronary arteries is the most frequent indication for lipid apheresis as well as homozygous familial hypercholesterolemia before the development of cardiovascular complications.In hyperlipoproteinemia (a) with progressive vessel disease, lipid apheresis is regularly accepted in Germany. The indication of apheresis in Refsum's disease and the chylomicronemia syndrome is described.

Indexed as

Blood Component RemovalChronic DiseaseHumansHyperlipoproteinemiasLipoprotein(a)Patient SelectionTreatment OutcomeLipoprotein(a)

Identifiers

PMID25686595
PMCPMC4361751
OpenAlexW267453021

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.