Evidence map›Paper›PMID 25685987›Full record

ReviewNutrients2015

Novel approaches to improve the intrinsic microbiological safety of powdered infant milk formula.

Robert M Kent, Gerald F Fitzgerald, Colin Hill, Catherine Stanton, R Paul Ross

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 88 citations in OpenAlex.

  1. Probiotics as a Barrier AgainstFoods (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Microorganisms · 2023
    Review
  8. Epidemiology of foodborne diseases caused byFrontiers in public health · 2023
    Article
  9. Inhibition ofFrontiers in microbiology · 2022
    Article
  10. Review
  11. Review
  12. Review
  13. Early life nutrition.Science progress · 2018
    Review
  14. Review
  15. Frontiers in microbiology · 2018
    Article
  16. Review
  17. Review
  18. Review
  19. Inhibition ofKorean journal for food science of animal resources · 2016
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Robert M KentTeagasc Food Research Centre, Moorepark, Fermoy, Cork EIRE, Ireland. robert.kent@teagasc.ie.
Gerald F FitzgeraldDepartment of Microbiology, University College Cork, Cork EIRE, Ireland. g.fitzgerald@ucc.ie.
Colin HillDepartment of Microbiology, University College Cork, Cork EIRE, Ireland. c.hill@ucc.ie.
Catherine StantonTeagasc Food Research Centre, Moorepark, Fermoy, Cork EIRE, Ireland. catherine.stanton@teagasc.ie.
R Paul RossDepartment of Microbiology, University College Cork, Cork EIRE, Ireland. p.ross@ucc.ie.
Alimentary Health (Ireland) · IETeagasc - The Irish Agriculture and Food Development Authority · IEUniversity College Cork · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human milk is recognised as the best form of nutrition for infants. However; in instances where breast-feeding is not possible, unsuitable or inadequate, infant milk formulae are used as breast milk substitutes. These formulae are designed to provide infants with optimum nutrition for normal growth and development and are available in either powdered or liquid forms. Powdered infant formula is widely used for convenience and economic reasons. However; current manufacturing processes are not capable of producing a sterile powdered infant formula. Due to their immature immune systems and permeable gastro-intestinal tracts, infants can be more susceptible to infection via foodborne pathogenic bacteria than other age-groups. Consumption of powdered infant formula contaminated by pathogenic microbes can be a cause of serious illness. In this review paper, we discuss the current manufacturing practices present in the infant formula industry, the pathogens of greatest concern, Cronobacter and Salmonella and methods of improving the intrinsic safety of powdered infant formula via the addition of antimicrobials such as: bioactive peptides; organic acids; probiotics and prebiotics.

Indexed as

Infant FormulaAnti-Infective AgentsFemaleFood ContaminationFood IndustryHumansInfantInfant FoodInfant, NewbornMalePeptidesPrebioticsProbioticsAnti-Infective AgentsPeptidesPrebiotics

Identifiers

PMID25685987
PMCPMC4344585
OpenAlexW2115305127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.