Evidence map›Paper›PMID 25685825›Full record

ArticleJournal of medical imaging (Bellingham, Wash.)2014

Region of interest based Hotelling observer for computed tomography with comparison to alternative methods.

Adrian A Sanchez, Emil Y Sidky, Xiaochuan Pan

Abstract read
In one paragraph

Article in Journal of medical imaging (Bellingham, Wash.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Adrian A SanchezThe University of Chicago, Department of Radiology, 5841 South Maryland Avenue, Chicago, Illinois 60615, United States.
Emil Y SidkyThe University of Chicago, Department of Radiology, 5841 South Maryland Avenue, Chicago, Illinois 60615, United States.
Xiaochuan PanThe University of Chicago, Department of Radiology, 5841 South Maryland Avenue, Chicago, Illinois 60615, United States ; The University of Chicago, Department of Radiation and Cellular Oncology, 5758 South Maryland Avenue, Chicago, Illinois 60615, United States.

Funding

RESEARCH TRAINING IN MEDICAL PHYSICST32EB002103 · NIBIB · UNIVERSITY OF CHICAGO · PI ARMATO, SAMUEL G. · 2003 to 2019
$4.7M
Targeted Imaging in Helical Cone-Beam CTR01EB000225 · NIBIB · UNIVERSITY OF CHICAGO · PI PAN, XIAOCHUAN · 2002 to 2014
$3.5M
Digital Specimen Tomosynthesis for Volumetric Imaging of Lumpectomy SpecimensR01EB018102 · NIBIB · UNIVERSITY OF CHICAGO · PI PAN, XIAOCHUAN · 2014 to 2017
$2.0M
Optimized Cone-Beam CT for Image-Guided Radiation TherapyR01CA120540 · NCI · UNIVERSITY OF CHICAGO · PI PAN, XIAOCHUAN · 2007 to 2011
$1.9M
Development of Advanced C-arm Cone-Beam CT for the Treatment of Liver CancerR01CA182264 · NCI · UNIVERSITY OF CHICAGO · PI PAN, XIAOCHUAN · 2014 to 2017
$1.8M
Limited Angle Image ReconstructionR01CA158446 · NCI · UNIVERSITY OF CHICAGO · PI SIDKY, EMIL Y · 2012 to 2015
$1.2M
Sparse-view C-arm Cone-beam CT for Guidance of Brain Aneurysm CoilingF31EB018742 · NIBIB · UNIVERSITY OF CHICAGO · PI SANCHEZ, ADRIAN ALBERTO · 2014 to 2014
$33k
NCI NIH HHS R01 CA120540NCI NIH HHS R01 CA158446NCI NIH HHS R01 CA182264NIBIB NIH HHS F31 EB018742NIBIB NIH HHS R01 EB000225NIBIB NIH HHS R01 EB018102NIBIB NIH HHS T32 EB002103
6 · The paper itself

Abstract

We compare several approaches to estimation of Hotelling observer (HO) performance in x-ray computed tomography (CT). We consider the case where the signal of interest is small so that the reconstructed image can be restricted to a small region of interest (ROI) surrounding the signal. This reduces the dimensionality of the image covariance matrix so that direct computation of HO metrics within the ROI is feasible. We propose that this approach is directly applicable to systems optimization in CT; however, many alternative approaches exist, which make computation of HO performance tractable through a range of approximations, assumptions, or estimation strategies. Here, we compare several of these methods, including the use of Laguerre-Gauss channels, discrete Fourier domain computation of the HO (which assumes noise stationarity), and two approaches to HO estimation through samples of noisy images. Since our method computes HO performance exactly within an ROI, this allows us to investigate the validity of the assumptions inherent in various common approaches to HO estimation, such as the stationarity assumption in the case of the discrete Fourier transform domain method.

Indexed as

Hotelling observerimage qualityimage reconstructionobjective assessment

Identifiers

PMID25685825
PMCPMC4326074

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.