Evidence map›Paper›PMID 25685613›Full record

ArticlePLoS currents2014

The UCSC Ebola Genome Portal.

Maximilian Haeussler, Donna Karolchik, Hiram Clawson, Brian J Raney, Kate R Rosenbloom, Pauline A Fujita, Angie S Hinrichs, Matthew L Speir, Chris Eisenhart, Ann S Zweig and 2 more

Open access · greenAbstract read
In one paragraph

Article in PLoS currents, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Maximilian HaeusslerCBSE, University of California Santa Cruz, Santa Cruz, California, USA.
Donna KarolchikCBSE, University of California Santa Cruz, Santa Cruz, California, USA.
Hiram ClawsonCBSE, University of California Santa Cruz, Santa Cruz, California, USA.
Brian J RaneyCBSE, University of California Santa Cruz, Santa Cruz, California, USA.
Kate R RosenbloomCBSE, University of California Santa Cruz, Santa Cruz, California, USA.
Pauline A FujitaCBSE, University of California Santa Cruz, Santa Cruz, California, USA.
Angie S HinrichsGenomics Institute, University of California Santa Cruz, Santa Cruz, California, USA.
Matthew L Speir
Chris EisenhartCBSE, University of California Santa Cruz, Santa Cruz, California, USA.
Ann S ZweigCBSE, University of California Santa Cruz, Santa Cruz, California, USA.
David HausslerCBSE, University of California Santa Cruz, Santa Cruz, California, USA.
W James KentCBSE, University of California Santa Cruz, Santa Cruz, California, USA.
University of California, Santa Cruz · US

Funding

The UCSC Genome BrowserU41HG002371 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI KENT, WILLIAM JAMES · 2012 to 2021
$36.6M
The UCSC Genome BrowserU24HG002371 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI Maximilian Haeussler · 2022 to 2026
$17.6M
NHGRI NIH HHS U24 HG002371NHGRI NIH HHS U41 HG002371
6 · The paper itself

Abstract

backgroundWith the Ebola epidemic raging out of control in West Africa, there has been a flurry of research into the Ebola virus, resulting in the generation of much genomic data.

methodsIn response to the clear need for tools that integrate multiple strands of research around molecular sequences, we have created the University of California Santa Cruz (UCSC) Ebola Genome Browser, an adaptation of our popular UCSC Genome Browser web tool, which can be used to view the Ebola virus genome sequence from GenBank and nearly 30 annotation tracks generated by mapping external data to the reference sequence. Significant annotations include a multiple alignment comprising 102 Ebola genomes from the current outbreak, 56 from previous outbreaks, and 2 Marburg genomes as an outgroup; a gene track curated by NCBI; protein annotations curated by UniProt and antibody-binding epitopes curated by IEDB. We have extended the Genome Browser's multiple alignment color-coding scheme to distinguish mutations resulting from non-synonymous coding changes, synonymous changes, or changes in untranslated regions. DISCUSSION: Our Ebola Genome portal at http://genome.ucsc.edu/ebolaPortal/ links to the Ebola virus Genome Browser and an aggregate of useful information, including a collection of Ebola antibodies we are curating.

Indexed as

ebolaebolavirusEBOVgenome analysisgenomics

Identifiers

PMID25685613
PMCPMC4318873
OpenAlexW1966504403

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.