Evidence map›Paper›PMID 25685311›Full record

ArticleChemical science2014

Non-Directed Allylic C-H Acetoxylation in the Presence of Lewis Basic Heterocycles.

Hasnain A Malik, Buck L H Taylor, John R Kerrigan, Jonathan E Grob, K N Houk, J Du Bois, Lawrence G Hamann, Andrew W Patterson

Abstract read
In one paragraph

Article in Chemical science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. C(spJournal of the American Chemical Society · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Palladium-Mediated CAngewandte Chemie (International ed. in English) · 2021
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Aliphatic C-H Oxidations for Late-Stage Functionalization.Journal of the American Chemical Society · 2018
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hasnain A MalikGlobal Discovery Chemistry, Novartis Institutes for BioMedical Research, Inc., Cambridge, Massachusetts 02139.
Buck L H TaylorDepartment of Chemistry and Biochemistry, University of California, Los Angeles, California 90095.
John R KerriganGlobal Discovery Chemistry, Novartis Institutes for BioMedical Research, Inc., Cambridge, Massachusetts 02139.
Jonathan E GrobGlobal Discovery Chemistry, Novartis Institutes for BioMedical Research, Inc., Cambridge, Massachusetts 02139.
K N HoukDepartment of Chemistry and Biochemistry, University of California, Los Angeles, California 90095.
J Du BoisDepartment of Chemistry, Stanford University, Stanford, California 94305.
Lawrence G HamannGlobal Discovery Chemistry, Novartis Institutes for BioMedical Research, Inc., Cambridge, Massachusetts 02139.
Andrew W PattersonGlobal Discovery Chemistry, Novartis Institutes for BioMedical Research, Inc., Cambridge, Massachusetts 02139.

Funding

Computational Investigation of Asymmetric Allylic Alkylation ReactionsF32GM106596 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TAYLOR, BUCK · 2013 to 2015
$122k
NIGMS NIH HHS F32 GM106596
6 · The paper itself

Abstract

We outline a strategy to enable non-directed Pd(II)-catalyzed C-H functionalization in the presence of Lewis basic heterocycles. In a high-throughput screen of two Pd-catalyzed C-H acetoxylation reactions, addition of a variety of

Identifiers

PMID25685311
PMCPMC4323382

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.