ReviewWorld journal of diabetes2015
Literature review on the management of diabetic foot ulcer.
Review in World journal of diabetes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03626623 (A Prospective, Randomized, Controlled Trial Comparing Cytal Wound Matrix 1-Layer to Standard of Care), which is not on this map. Cited by 205 papers, 12 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective, Randomized, Controlled Trial Comparing Cytal Wound Matrix 1-Layer to Standard of Care (SOC) in the Management of Diabetic Foot Ulcers (DFUs)
Who cites it
205 citing papers in PubMed, 12 syntheses or guidelines pooled it, 587 citations in OpenAlex.
- Systematic review and meta-analysis of diabetic foot ulcers and associated factors among adults in Ethiopia.Archives of public health = Archives belges de sante publique · 2025Pooled it
- The role of vitamin D in diabetic foot ulcer; an umbrella review of meta-analyses.Frontiers in nutrition · 2024Pooled it
- Efficacy of MSC-derived small extracellular vesicles in treating type II diabetic cutaneous wounds: a systematic review and meta-analysis of animal models.Frontiers in endocrinology · 2024Pooled it
- A meta-analysis on the efficacy of vacuum sealing drainage combined with autologous platelet-rich plasma in the treatment of Grade 2 and Grade 3 diabetic foot ulcers.International wound journal · 2023Pooled it
- The association between micronutrient levels and diabetic foot ulcer: A systematic review with meta-analysis.Frontiers in endocrinology · 2023Pooled it
- Platelet-rich plasma for the treatment of diabetic foot ulcer: a systematic review.Frontiers in endocrinology · 2023Pooled it
- MSC-Derived Extracellular Vesicles to Heal Diabetic Wounds: a Systematic Review and Meta-Analysis of Preclinical Animal Studies.Stem cell reviews and reports · 2022Pooled it
- A Net Meta-Analysis of the Effectiveness of Different Types of Dressings in the Treatment of Diabetic Foot.Computational and mathematical methods in medicine · 2022Pooled it
- Efficacy of hyperbaric oxygen therapy for diabetic foot ulcer, a systematic review and meta-analysis of controlled clinical trials.Scientific reports · 2021Pooled it
- Risk factors for diabetic foot complications in type 2 diabetes-A systematic review.Endocrinology, diabetes & metabolism · 2021Pooled it
- Prevention, assessment, diagnosis and management of diabetic foot based on clinical practice guidelines: A systematic review.Medicine · 2019Pooled it
- The association between diabetes and dermal microvascular dysfunction non-invasively assessed by laser Doppler with local thermal hyperemia: a systematic review with meta-analysis.Cardiovascular diabetology · 2017Pooled it
- Sitagliptin, a DPP-4 Inhibitor, Effectively Promotes the Healing of Diabetic Foot Ulcer: A Randomized Controlled Trial.Journal of diabetes · 2025Trial
- Efficacy of the Novel Formulation of Topical Liothyronine and Liothyronine-insulin in Mild to Moderate Diabetic Foot Ulcer: A Randomized, Triple-blind Clinical Trial.Current medicinal chemistry · 2024Trial
- Topical Esmolol Hydrochloride as a Novel Treatment Modality for Diabetic Foot Ulcers: A Phase 3 Randomized Clinical Trial.JAMA network open · 2023Trial
- The effects of different accumulated pressure-time integral stimuli on plantar blood flow in people with diabetes mellitus.BMC musculoskeletal disorders · 2021Trial
- Trial
- The assessment of Buerger's exercise on dorsal foot skin circulation in patients with vasculopathic diabetic foot ulcer by using wireless near-infrared spectroscope: a cohort prospective study.Lasers in medical science · 2018Trial
- Treatment of diabetic foot ulcers with Therapeutic Magnetic Resonance (TMR®) improves the quality of granulation tissue.European journal of histochemistry : EJH · 2017Trial
- Healing the Sole: Combining Natural Plant Extracts and Conventional Drugs in Wound Delivery Systems for Diabetic Foot Ulcer Treatment.International journal of molecular sciences · 2026Review
145 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetic foot ulcer (DFU) is the most costly and devastating complication of diabetes mellitus, which affect 15% of diabetic patients during their lifetime. Based on National Institute for Health and Clinical Excellence strategies, early effective management of DFU can reduce the severity of complications such as preventable amputations and possible mortality, and also can improve overall quality of life. The management of DFU should be optimized by using a multidisciplinary team, due to a holistic approach to wound management is required. Based on studies, blood sugar control, wound debridement, advanced dressings and offloading modalities should always be a part of DFU management. Furthermore, surgery to heal chronic ulcer and prevent recurrence should be considered as an essential component of management in some cases. Also, hyperbaric oxygen therapy, electrical stimulation, negative pressure wound therapy, bio-engineered skin and growth factors could be used as adjunct therapies for rapid healing of DFU. So, it's suggested that with appropriate patient education encourages them to regular foot care in order to prevent DFU and its complications.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.