Evidence map›Paper›PMID 25685109›Full record

ArticleCurrent sexual health reports2014

The implications of low testosterone on mortality in men.

Molly M Shores

Abstract read
In one paragraph

Article in Current sexual health reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Molly M ShoresVA Puget Sound Health Care System, Seattle, WA ; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA.

Funding

Adverse Events Associated with Testosterone Treatment in Hypogonadal MenR01AG042934 · NIA · SEATTLE INST FOR BIOMEDICAL/CLINICAL RES · PI SHORES, MOLLY MCDONOUGH, WALSH, THOMAS JAMES · 2012 to 2013
$385k
NIA NIH HHS R01 AG042934
6 · The paper itself

Abstract

Testosterone levels in men slowly decline with aging and also decline more abruptly due to medical illness or medications. Prescriptions for testosterone have increased dramatically over the past decade, since a testosterone-gel formulation was approved and since numerous studies reported an association between low serum testosterone and increased mortality. However, recent observational studies of testosterone treatment have reported conflicting results with some studies reporting decreased risks for mortality while others reported increased mortality risks with testosterone treatment. This paper will summarize recent studies of low serum testosterone and mortality and testosterone treatment and mortality and what the potential implications of these studies are for the clinician.

Indexed as

AndrogensCardiovascular eventsHypogonadismMortalityTestosteroneTestosterone treatment

Identifiers

PMID25685109
PMCPMC4323275

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.