Evidence map›Paper›PMID 25684950›Full record

ArticleWorld journal of gastroenterology2015

Retrospective analysis of extra-gastrointestinal stromal tumors.

Jun Ho Yi, Byeong-Bae Park, Jung Hun Kang, In Gyu Hwang, Dong Bok Shin, Sun Jin Sym, Hee Kyung Ahn, Soon Il Lee, Do Hyoung Lim, Keon Woo Park and 3 more

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Domestic research on extra-gastrointestinal stromal tumors: A ten-year review.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Review
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  17. Perianal extragastrointestinal stromal tumor.Korean journal of clinical oncology · 2020
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 2 countries.

Jun Ho YiJun Ho Yi, Byeong-Bae Park, Division of Hematology-Oncology, Department of Internal Medicine, Hanyang University Seoul Hospital, Seoul 133-792, South Korea.
Byeong-Bae ParkJun Ho Yi, Byeong-Bae Park, Division of Hematology-Oncology, Department of Internal Medicine, Hanyang University Seoul Hospital, Seoul 133-792, South Korea.
Jung Hun KangJun Ho Yi, Byeong-Bae Park, Division of Hematology-Oncology, Department of Internal Medicine, Hanyang University Seoul Hospital, Seoul 133-792, South Korea.
In Gyu HwangJun Ho Yi, Byeong-Bae Park, Division of Hematology-Oncology, Department of Internal Medicine, Hanyang University Seoul Hospital, Seoul 133-792, South Korea.
Dong Bok ShinJun Ho Yi, Byeong-Bae Park, Division of Hematology-Oncology, Department of Internal Medicine, Hanyang University Seoul Hospital, Seoul 133-792, South Korea.
Sun Jin SymJun Ho Yi, Byeong-Bae Park, Division of Hematology-Oncology, Department of Internal Medicine, Hanyang University Seoul Hospital, Seoul 133-792, South Korea.
Hee Kyung AhnJun Ho Yi, Byeong-Bae Park, Division of Hematology-Oncology, Department of Internal Medicine, Hanyang University Seoul Hospital, Seoul 133-792, South Korea.
Soon Il LeeJun Ho Yi, Byeong-Bae Park, Division of Hematology-Oncology, Department of Internal Medicine, Hanyang University Seoul Hospital, Seoul 133-792, South Korea.
Do Hyoung LimJun Ho Yi, Byeong-Bae Park, Division of Hematology-Oncology, Department of Internal Medicine, Hanyang University Seoul Hospital, Seoul 133-792, South Korea.
Keon Woo ParkJun Ho Yi, Byeong-Bae Park, Division of Hematology-Oncology, Department of Internal Medicine, Hanyang University Seoul Hospital, Seoul 133-792, South Korea.
Young-Woong WonJun Ho Yi, Byeong-Bae Park, Division of Hematology-Oncology, Department of Internal Medicine, Hanyang University Seoul Hospital, Seoul 133-792, South Korea.
Sung Hee LimJun Ho Yi, Byeong-Bae Park, Division of Hematology-Oncology, Department of Internal Medicine, Hanyang University Seoul Hospital, Seoul 133-792, South Korea.
Se Hoon ParkJun Ho Yi, Byeong-Bae Park, Division of Hematology-Oncology, Department of Internal Medicine, Hanyang University Seoul Hospital, Seoul 133-792, South Korea.
Deleted Institution

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the clinicopathologic features of patients with extra-gastrointestinal stromal tumors (EGISTs) in South Korea.

methodsA total of 51 patients with an EGIST were identified. The clinicopathologic features, including sex, age, location, tumor size, histology, mitotic rate, immunohistochemical features, genetic status and survival data, were analyzed.

resultsThe median age was 55 years (range: 29-80 years), and male:female ratio was 1:1.04. The most common site was in the mesentery (n = 15) followed by the retroperitoneum (n = 13) and omentum (n = 8). The median tumor size was 9.0 cm (range: 2.6-30.0 cm) and the median mitotic rate was 5.0/50HPF. (1/50 - 185/50). KIT was analyzed in 16, which revealed 10 cases with wild-type KIT and 6 cases with an exon 11 mutation. Among 51 patients, 31 patients had undergone surgery, and 10 had unresectable disease and had taken palliative imatinib, which resulted in 22.7 mo of progression-free survival. Of the patients who had undergone surgery, 18 did not take adjuvant imatinib, and 8 of these were categorized as "high risk" according to the risk criteria. However, the relapse-free survival was not different (P = 0.157) between two groups.

conclusionBecause the biologic behaviors of GISTs differ according to the location of the tumor, a more stratified strategy is required for managing EGISTs including incorporation of molecular features.

Indexed as

AdultAgedAged, 80 and overBiomarkers, TumorDisease-Free SurvivalDisease ProgressionDNA Mutational AnalysisFemaleGastrointestinal Stromal TumorsHumansImmunohistochemistryMaleMiddle AgedMitotic IndexMutationNeoplasm Recurrence, LocalBiomarkers, TumorProto-Oncogene Proteins c-kitGastrointestinal stromal tumorImatinibPrognostic factorRisk factorSurvival

Identifiers

PMID25684950
PMCPMC4323461
OpenAlexW2161582385

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.