Evidence map›Paper›PMID 25684779›Full record

ArticleChemical engineering science2015

Controlled Drug Release from Pharmaceutical Nanocarriers.

Jinhyun Hannah Lee, Yoon Yeo

Abstract read
In one paragraph

Article in Chemical engineering science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 188 papers.

0numbers the graph read from it
0cells of the map it votes in
188citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

188 citing papers in PubMed, 574 citations in OpenAlex.

  1. Review
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  7. Nano-Enabled Advances in Tea Tree Essential Oil (Materials (Basel, Switzerland) · 2026
    Review
  8. Article
  9. Article
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  12. Article
  13. Advances in Drug Delivery Systems for Boswellic Acids fromInternational journal of molecular sciences · 2026
    Review
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  15. Review
  16. Article
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  19. Article
  20. Article

128 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Jinhyun Hannah LeeCollege of Pharmacy and Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA.
Yoon YeoCollege of Pharmacy and Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA ; Biomedical Research Institute, Korea Institute of Science and Technology, Hwarangno 14-gil 5, Seongbuk-gu, Seoul 136-791, Republic of Korea.
Purdue University West Lafayette · US

Funding

Environmentally-adaptive nanoparticles with focal irradiation for cancer therapyR01EB017791 · NIBIB · PURDUE UNIVERSITY · PI YEO, YOON · 2014 to 2018
$1.6M
NIBIB NIH HHS R01 EB017791
6 · The paper itself

Abstract

Nanocarriers providing spatiotemporal control of drug release contribute to reducing toxicity and improving therapeutic efficacy of a drug. On the other hand, nanocarriers face unique challenges in controlling drug release kinetics, due to the large surface area per volume ratio and the short diffusion distance. To develop nanocarriers with desirable release kinetics for target applications, it is important to understand the mechanisms by which a carrier retains and releases a drug, the effects of composition and morphology of the carrier on the drug release kinetics, and current techniques for preparation and modification of nanocarriers. This review provides an overview of drug release mechanisms and various nanocarriers with a specific emphasis on approaches to control the drug release kinetics.

Indexed as

controlled releasedrug deliverydrug release kineticsdrug release mechanismsNanocarriers

Identifiers

PMID25684779
PMCPMC4322773
OpenAlexW2007755698

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.