Evidence map›Paper›PMID 25684681›Full record

ArticleScientific reports2015

Visualization of endogenous and exogenous hydrogen peroxide using a lysosome-targetable fluorescent probe.

Dabin Kim, Gyoungmi Kim, Sang-Jip Nam, Jun Yin, Juyoung Yoon

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
8.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 106 citations in OpenAlex.

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  20. Recent Progress in Fluorescent Imaging Probes.Sensors (Basel, Switzerland) · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Dabin KimDepartment of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Korea.
Gyoungmi KimDepartment of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Korea.
Sang-Jip NamDepartment of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Korea.
Jun Yin1] Department of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Korea [2] Key Laboratory of Pesticide and Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan. 430079, P. R. China.
Juyoung YoonDepartment of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Korea.
Ewha Womans University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reactive oxygen species (ROS) play crucial roles in diverse physiological processes; therefore, the efficient detection of ROS is very crucial. In this study, we report a boronate-based hydrogen peroxide (H2O2) probe having naphthalimide fluorophore. This probe also contained a morpholine moiety as a directing group for lysosome. The recognition property indicated that the probe exhibited high selectivity towards H2O2 not only in the solution but also in the living cells. Furthermore, it was used to monitor the level of endogenous and exogenous H2O2. These results support that the probe can function as an efficient indicator to detect H2O2.

Indexed as

Fluorescent DyesHeLa CellsHumansHydrogen PeroxideLysosomesMolecular ImagingReactive Oxygen SpeciesFluorescent DyesHydrogen PeroxideReactive Oxygen Species

Identifiers

PMID25684681
PMCPMC4329546
OpenAlexW2092965013

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.