Evidence map›Paper›PMID 25683714›Full record

ArticleCell reports2015

Tiger Swallowtail Genome Reveals Mechanisms for Speciation and Caterpillar Chemical Defense.

Qian Cong, Dominika Borek, Zbyszek Otwinowski, Nick V Grishin

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
11.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 90 citations in OpenAlex.

  1. Article
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  5. What one genus of showy moths can say about migration, adaptation, and wing pattern.Proceedings of the National Academy of Sciences of the United States of America · 2024
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  6. Taxonomic advances driven by the genomic analysis of butterflies.The taxonomic report of the International Lepidoptera Survey · 2024
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  7. Complete mitochondrial genome data and phylogenetic analysis ofMitochondrial DNA. Part B, Resources · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Butterfly classification and species discovery using genomics.The taxonomic report of the International Lepidoptera Survey · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Genomics Reveals the Origins of Historical Specimens.Molecular biology and evolution · 2021
    Article
  17. Article
  18. Article
  19. Speciation in North AmericanSystematic entomology · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Qian CongDepartment of Biophysics and Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8816, USA.
Dominika BorekDepartment of Biophysics and Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8816, USA.
Zbyszek OtwinowskiDepartment of Biophysics and Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8816, USA.
Nick V GrishinHoward Hughes Medical Institute, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9050, USA; Department of Biophysics and Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8816, USA. Electronic address: grishin@chop.swmed.edu.
The University of Texas Southwestern Medical Center · USHoward Hughes Medical Institute · US

Funding

Computational methods for structural-functional studies of proteinsR01GM094575 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI GRISHIN, NICK V. · 2010 to 2017
$2.4M
Computational analysis of proteinsR35GM127390 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI GRISHIN, NICK V. · 2018 to 2022
$1.5M
NIGMS NIH HHS R01 GM094575NIGMS NIH HHS R35 GM127390
6 · The paper itself

Abstract

Predicting phenotype from genotype represents the epitome of biological questions. Comparative genomics of appropriate model organisms holds the promise of making it possible. However, the high heterozygosity of many Eukaryotes currently prohibits assembling their genomes. Here, we report the 376 Mb genome sequence of Papilio glaucus (Pgl), the first sequenced genome from the Papilionidae family. We obtained the genome from a wild-caught specimen using a cost-effective strategy that overcomes the high (2%) heterozygosity problem. Comparative analyses suggest the molecular bases of various phenotypic traits, including terpene production in the Papilionidae-specific organ, osmeterium. Comparison of Pgl and Papilio canadensis transcriptomes reveals mutation hotspots (4% genes) associated with their divergence: four key circadian clock proteins are enriched in inter-species mutations and likely responsible for the difference in pupal diapause. Finally, the Pgl genome confirms Papilio appalachiensis as a hybrid of Pgl and Pca, but suggests it inherited 3/4 of its genes from Pca.

Identifiers

PMID25683714
PMCPMC8935626
OpenAlexW2039752368

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.