Evidence map›Paper›PMID 2568335›Full record

ArticleImmunogenetics1989

A mouse chromosome 17 gene encodes a testes-specific transcript with unusual properties.

N Sarvetnick, J Y Tsai, H Fox, S H Pilder, L M Silver

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Immunogenetics, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. TCTE1 is a conserved component of the dynein regulatory complex and is required for motility and metabolism in mouse spermatozoa.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  3. Genomic mapping of intracisternal A-particle proviral elements.Mammalian genome : official journal of the International Mammalian Genome Society · 1993
    Article
  4. Mouse chromosome 17.Mammalian genome : official journal of the International Mammalian Genome Society · 1992
    Review
  5. Comparative map for mice and humans.Mammalian genome : official journal of the International Mammalian Genome Society · 1992
    Review
  6. Delineation of the t complex on mouse chromosome 17 by in situ hybridization.Mammalian genome : official journal of the International Mammalian Genome Society · 1992
    Article
  7. Mapping of six DNA markers on mouse chromosome 17.Mammalian genome : official journal of the International Mammalian Genome Society · 1992
    Article
  8. Limits of the distal inversion in the t complex of the house mouse: evidence from linkage disequilibria.Mammalian genome : official journal of the International Mammalian Genome Society · 1991
    Article
  9. Article
  10. Comparative map for mice and humans.Mammalian genome : official journal of the International Mammalian Genome Society · 1991
    Review
  11. List of cloned mouse genes with unique expression patterns during spermatogenesis.Mammalian genome : official journal of the International Mammalian Genome Society · 1991
    Article
  12. Mouse chromosome 17.Mammalian genome : official journal of the International Mammalian Genome Society · 1991
    Review
  13. Maps of mouse chromosome 17: first report. Committee for Mouse Chromosome 17.Mammalian genome : official journal of the International Mammalian Genome Society · 1991
    Review
  14. Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

N SarvetnickCold Spring Harbor Laboratory, NY 11724.
J Y Tsai
H Fox
S H Pilder
L M Silver
Princeton University · USCold Spring Harbor Laboratory · US

Funding

T BOX GENES: EVOLUTION, MOLECULAR BIOLOGY, AND GENETICSR37HD020275 · NICHD · PRINCETON UNIVERSITY · PI SILVER, LEE M · 1995 to 2003
$1.7M
ORGANIZATION AND EXPRESSION OF THE MOUSE T COMPLEXR01HD020275 · NICHD · PRINCETON UNIVERSITY · PI SILVER, LEE M · 1985 to 1994
–
NICHD NIH HHS HD20275
6 · The paper itself

Abstract

We have characterized a novel mouse gene (D17Si11) on chromosome 17 that expresses a major transcript observed uniquely in the testes. The D17Si11 locus has been mapped to the central region of chromosome 17 between H-2 and C3. Sequence analysis demonstrates several unusual features of this locus and its transcript: first is the presence of complementary sets of alternating purine and pyrimidine residues within the 3' region of the transcript that could form double-stranded, hairpin-like secondary structures with properties similar to that of Z-DNA; second is the existence of a hypothetical, long open reading frame in the nucleotide strand that is complementary to the testes transcripts. This complementary strand open reading frame is three times the size of the longest potential open reading frame present in the transcript itself. Although a function for D17Si11 has yet to be determined, the gene is relatively nonpolymorphic in mice and appears conserved in mammals.

Indexed as

Chromosome MappingAmino Acid SequenceAnimalsBase SequenceCell DifferentiationCloning, MolecularDNAMaleMiceMolecular Sequence DataPolymorphism, Restriction Fragment LengthProteinsSequence Homology, Nucleic AcidSpermatozoaTestisDNAProteinsTCTE1 protein, mouse

Identifiers

PMID2568335
OpenAlexW1967499398

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.