ArticleWound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
Postoperative wound dehiscence: Predictors and associations.
Article in Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 87 citations in OpenAlex.
- Suture choice to reduce occurrence of surgical site infection, hernia, wound dehiscence and sinus/fistula: a network meta-analysis.Annals of the Royal College of Surgeons of England · 2019Pooled it
- Efficacy and safety of epidermal cell regeneration for postoperative non-healing wounds: a randomized, partially blinded, parallel-controlled trial.Stem cell research & therapy · 2025Trial
- Comparison of surgical wound infection and dehiscence following the use of two methods of nylon sutures and skin staples in staples in diabetic mellitus patients undergoing total knee arthroplasty surgery: a randomized clinical trial study.BMC musculoskeletal disorders · 2025Trial
- Comparison of two surgical suture techniques in uvulopalatopharyngoplasty and expansion sphincter pharyngoplasty.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018Trial
- Dexamethasone reduces postoperative pain while delays wound healing in an animal model: Involvement of the NLRP3/Caspase-1/IL-1β pathway.BMC anesthesiology · 2026Article
- Clinical Study on Masquelet Membrane Induction Technique Combined With Free Skin Grafting for the Treatment of Chronic Refractory Wounds With Bone/Tendon Exposure in Aged Patients.International wound journal · 2026Article
- The Split-Level Folding, Step-Type Tension-Relieving Suture Technique Improves the Wound Tensile Strength.Aesthetic plastic surgery · 2026Article
- Risk Factors and Predictive Accuracy of the Rotterdam Risk Index for Wound Dehiscence Following Abdominal Surgery.Cureus · 2025Article
- Use of Continuous Topical Oxygen Therapy to Treat Lower-Extremity Surgical Wound Dehiscence: A Retrospective Review.Eplasty · 2025Article
- Bacteria-Derived Cellulose Membranes Modified with Graphene Oxide-Silver Nanoparticles for Accelerating Wound Healing.ACS applied bio materials · 2024Article
- Review
- Perioperative Outcomes, Comorbidities, and Complications following Total Shoulder Arthroplasty in Wheelchair Users: A Retrospective Cohort Analysis of a Nationwide Database.Journal of clinical medicine · 2023Article
- Prevalence of preoperative opioid usage and its impact on postoperative outcomes: a retrospective cohort study.Journal of anesthesia · 2023Article
- Incidence and impact of surgical site complications on length of stay and cost of care for patients undergoing open procedures.Surgery open science · 2023Article
- Risk factors for wound healing complications after revascularization for MMD with complete Y-shaped incision.Scientific reports · 2023Observational
- An Updated Review of Hypertrophic Scarring.Cells · 2023Review
- Topical vanadate improves tensile strength and alters collagen organisation of excisional wounds in a mouse model.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2023Article
- Incidence and risk factors for surgical wound complications in women with body mass index >30 kg/mAJOG global reports · 2022Article
- Article
- Microangiopathy in Inflammatory Diseases-Strategies in Surgery of the Lower Extremity.Life (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
The Agency for Healthcare Research and Quality patient safety indicators (PSI) were developed as a metric of hospital complication rates. PSI-14 measures postoperative wound dehiscence and specifically how often a surgical wound in the abdominal or pelvic area fails to heal after abdominopelvic surgery. Wound dehiscence is estimated to occur in 0.5-3.4% of abdominopelvic surgeries, and carries a mortality of up to 40%. Postoperative wound dehiscence has been adopted as a surrogate safety outcome measure as it impacts morbidity, length of stay, healthcare costs and readmission rates. Postoperative wound dehiscence cases from the Nationwide Inpatient Sample demonstrate 9.6% excess mortality, 9.4 days of excess hospitalization and $40,323 in excess hospital charges relative to matched controls. The purpose of the current study was to investigate the associations between PSI-14 and measurable medical and surgical comorbidities using the Explorys technology platform to query electronic health record data from a large hospital system serving a diverse patient population in the Washington, DC and Baltimore, MD metropolitan areas. The study population included 25,636 eligible patients who had undergone abdominopelvic surgery between January 1, 2008 and December 31, 2012. Of these cases, 786 (2.97%) had postoperative wound dehiscence. Patient-associated comorbidities were strongly associated with PSI-14, suggesting that this indicator may not solely be an indicator of hospital safety. There was a strong association between PSI-14 and opioid use after surgery and this finding merits further investigation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.