ArticleAnnals of epidemiology2015
Oxidative balance score as predictor of all-cause, cancer, and noncancer mortality in a biracial US cohort.
Article in Annals of epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
52 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A Review ofNutrients · 2019Pooled it
- Long-Term Exposure to Air Pollutants and Cancer Mortality: A Meta-Analysis of Cohort Studies.International journal of environmental research and public health · 2018Pooled it
- Association between an oxidative balance score and mortality: a prospective analysis in the SUN cohort.European journal of nutrition · 2023Trial
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- Article
- The impact of diet and lifestyle-related oxidative stress on asthma outcomes: a longitudinal NHANES analysis.Annals of medicine · 2025Article
- Assessing the Impact of Composite Dietary Antioxidant Index on Gastric Cancer Risk: A Case-Control Study in Southeast China.Nutrients · 2025Article
- Association between dietary oxidative balance scores and myocardial infarction in diabetic patients: insights from NHANES 1999-2018.BMC public health · 2025Article
- Association between oxidative balance score and risk of postpartum depression in Iranian women: a prospective cohort study.Scientific reports · 2025Article
- Association of oxidative balance score with incident cardiovascular disease in patients with type 2 diabetes: findings of the UK Biobank study.European journal of nutrition · 2025Article
- Oxidative Balance Score Calculated Using Different Methods and Its Associations with Colorectal Cancer Risk.Nutrients · 2025Article
- Oxidative balance score and its association with chronic inflammatory airway diseases and mortality: a population-based study.Frontiers in nutrition · 2025Article
- Association between oxidative balance score and allergic rhinitis in American adults: a cross-sectional study.Frontiers in nutrition · 2025Article
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- Relationship between oxidative balance score and health-related quality of life in Korean adults.PloS one · 2025Article
- The association between Dietary Oxidative Balance Score and muscle strength: NHANES 2011-2014.Frontiers in nutrition · 2025Article
- Association between oxidative balance score and all-cause and cancer-specific mortality among cancer survivors.Frontiers in immunology · 2025Observational
- Association of oxidative balance score with all-cause and cardiovascular mortality in overweight and obese.Frontiers in nutrition · 2025Article
- Association of oxidative balance score with all-cause mortality among individuals with chronic kidney disease: a cohort study.Journal of health, population, and nutrition · 2024Article
- Association between oxidative balance scores and all-cause and cardiovascular disease-related mortality in patients with type 2 diabetes: data from the national health and nutrition examination survey (2007-2018).BMC public health · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
purposeWe previously proposed an oxidative balance score (OBS) that combines pro- and anti-oxidant exposures to represent the overall oxidative balance status of an individual. In this study, we investigated associations of the OBS with all-cause and cause-specific mortality, and explored alternative OBS weighting methods in the Reasons for Geographic and Racial Differences in Stroke Study cohort.
methodsThe OBS was calculated by combining information from 14 a priori selected pro- and anti-oxidant factors and then divided into quartiles with the lowest quartile (predominance of pro-oxidants) as reference. Cox proportional hazard models were used to estimate adjusted hazard ratios and 95% confidence intervals for each OBS category compared with the reference.
resultsOver a median 5.8 years of follow-up, 2079 of the 21,031 participants died. The multivariable-adjusted hazard ratios (95% confidence interval) for all-cause, cancer, and noncancer mortality for those in the highest versus the lowest equal-weighting OBS quartile were 0.70 (0.61-0.81), 0.50 (0.37-0.67), and 0.77 (0.66-0.89), respectively (P trend < .01 for all). Similar results were observed with all weighting methods.
conclusionsThese results suggest that individuals with a greater balance of antioxidant to pro-oxidant lifestyle exposures may have lower mortality.
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