Evidence map›Paper›PMID 25682210›Full record

ArticleJournal of pediatric psychology2015

Interpretability of the PedsQL™ Gastrointestinal Symptoms Scales and Gastrointestinal Worry Scales in Pediatric Patients With Functional and Organic Gastrointestinal Diseases.

James W Varni, Cristiane B Bendo, Robert J Shulman, Mariella M Self, Samuel Nurko, James P Franciosi, Miguel Saps, Shehzad Saeed, George M Zacur, Chelsea Vaughan Dark and 2 more

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In one paragraph

Article in Journal of pediatric psychology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Patient-Reported Long-Term Gastrointestinal Outcomes in Children with Omphalocele and Gastroschisis: A PedsQL GI Module Study.European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie · 2026
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  19. Perceived medication adherence barriers mediating effects between gastrointestinal symptoms and health-related quality of life in pediatric inflammatory bowel disease.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

James W VarniDepartment of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah Department of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah jvarni@arch.tamu.edu.
Cristiane B BendoDepartment of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah.
Robert J ShulmanDepartment of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah.
Mariella M SelfDepartment of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah Department of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah.
Samuel NurkoDepartment of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah.
James P FranciosiDepartment of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah.
Miguel SapsDepartment of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah.
Shehzad SaeedDepartment of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah.
George M ZacurDepartment of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah.
Chelsea Vaughan DarkDepartment of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah.
John F PohlDepartment of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah.
Pediatric Quality of Life Inventory™ Gastrointestinal Symptoms Module Testing Study Consortium

Funding

LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., KISSELA, BRETT M · 2015 to 2024
$37.5M
Cincinnati Center for Clinical and Translational Sciences and TrainingUL1TR000077 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., TSEVAT, JOEL · 2012 to 2014
$9.9M
NCATS NIH HHS UL1 TR000077NCATS NIH HHS UL1 TR001425
6 · The paper itself

Abstract

objectiveThe present study investigates the clinical interpretability of the Pediatric Quality of Life Inventory™ (PedsQL™) Gastrointestinal Symptoms Scales and Worry Scales in pediatric patients with functional gastrointestinal disorders or organic gastrointestinal diseases in comparison with healthy controls.

methodsThe PedsQL™ Gastrointestinal Scales were completed by 587 patients with gastrointestinal disorders/diseases and 685 parents, and 513 healthy children and 337 parents. Minimal important difference (MID) scores were derived from the standard error of measurement (SEM). Cut-points were derived based on one and two standard deviations (SDs) from the healthy reference means.

resultsThe percentages of patients below the scales' cut-points were significantly greater than the healthy controls (most p values ≤ .001). Scale scores 2 SDs from the healthy reference means were within the range of scores for pediatric patients with a gastrointestinal disorder. MID values were generated using the SEM.

conclusionsThe findings support the clinical interpretability of the new PedsQL™ Gastrointestinal Symptoms Scales and Worry Scales.

Indexed as

Attitude to HealthAdolescentAnxietyChildChild, PreschoolFemaleGastrointestinal DiseasesHumansMaleParentsPediatricsPsychometricsQuality of LifeReproducibility of ResultsSurveys and Questionnairesgastrointestinal symptomsminimal important difference; patient-reported outcomesPedsQL.

Identifiers

PMID25682210
PMCPMC4469917

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