ArticleClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2015
Risk of Colorectal and Other Cancers in Patients With Serrated Polyposis.
Article in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 27 citations in OpenAlex.
- [Hereditary colorectal cancer].Pathologie (Heidelberg, Germany) · 2026Review
- Serrated Polyposis Syndrome: A Narrative Review from Clinical Recognition to Risk-Adapted Cancer Prevention.International journal of general medicine · 2026Review
- Hereditary Colorectal Cancer Syndromes: Small Bowel Cancer Risk and Endoscopic Surveillance Strategies.Diagnostics (Basel, Switzerland) · 2025Review
- Cost-effectiveness analysis of alternative colorectal cancer screening strategies in high-risk individuals.Therapeutic advances in gastroenterology · 2021Article
- Novel Genetic Causes of Gastrointestinal Polyposis Syndromes.The application of clinical genetics · 2021Review
- Diagnosis, epidemiology and management of serrated polyposis syndrome: a comprehensive review of the literature.American journal of translational research · 2021Review
- Serrated Polyposis Syndrome with a Synchronous Colon Adenocarcinoma Treated by an Endoscopic Mucosal Resection.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2020Article
- Cost-effectiveness analysis of alternative colon cancer screening strategies in the context of the French national screening program.Therapeutic advances in gastroenterology · 2020Article
- Gastrointestinal Polyposis in Pediatric Patients.Journal of pediatric gastroenterology and nutrition · 2019Review
- Serrated Polyposis Syndrome in a Single-Center 10-Year Experience.Balkan medical journal · 2018Article
- Serrated Polyps of Colon and Rectum: a Clinicopathologic Review.Journal of gastrointestinal cancer · 2017Review
- Sessile Serrated Adenomas: How to Detect, Characterize and Resect.Gut and liver · 2017Review
- A retrospective study on pathological and clinical characteristics of 52 cases with the colorectal serrated polyp.Pakistan journal of medical sciencesArticle
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Authors and funding
11 authors at 4 institutions in 3 countries.
Funding
Abstract
Patients with serrated polyposis develop multiple colorectal hyperplastic and/or serrated sessile adenomas/polyps. We investigated the risk of colorectal and other cancers by analyzing data from 64 patients with serrated polyposis (mean age at diagnosis, 54 y; 41% men; 92% white) listed in the Johns Hopkins Polyposis Registry. Medical, endoscopic, and histopathology reports were evaluated. Six patients (9.4%) had a history of colorectal cancer, diagnosed at a mean age of 56 years; 6 additional patients (9.4%) had at least 1 advanced colorectal adenoma. Extracolonic cancers were found in 16% of the study population. The standard incidence ratio for colorectal cancer in patients with serrated polyposis was 18.72 (95% confidence interval, 6.87-40.74) and for extracolonic cancer was 31.20 (95% confidence interval, 14.96-57.37), compared with the Surveillance, Epidemiology, and End Results population. Patients with serrated polyposis therefore have a high risk for colorectal cancer and require vigilant colorectal surveillance, starting at the time of diagnosis of serrated polyposis. The risk of extracolonic cancer also appears to be increased, but this requires further evaluation.
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