Trial reportParasitology research2015
Efficacy of Broadline against Capillaria aerophila lungworm infection in cats.
Trial report in Parasitology research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Zoonotic Enteric Nematodes and Dermatophytes in Cat Cafés: An Investigation in the Bangkok Metropolitan Area, Thailand.Veterinary sciences · 2024Article
- Cat Respiratory Nematodes: Current Knowledge, Novel Data and Warranted Studies on Clinical Features, Treatment and Control.Pathogens (Basel, Switzerland) · 2021Review
- Efficacy of milbemycin oxime/afoxolaner chewable tablets (NEXGARD SPECTRAParasites & vectors · 2021Article
- A case of a dog refractory to different treatments for pulmonary capillariasis.Parasitology research · 2021Article
- What the fox? CrypticCurrent research in parasitology & vector-borne diseases · 2021Article
- Efficacy of a novel topical combination of esafoxolaner, eprinomectin and praziquantel in cats against Toxocara cati and Dipylidium caninum.Parasite (Paris, France) · 2021Article
- Efficacy of a topical combination of eprinomectin, praziquantel, fipronil and (S)-methoprene against developing and adultVeterinary parasitology: X · 2020Article
- Clinical-parasitological Screening for Respiratory Capillariosis in Cats in Urban Environments.Helminthologia · 2020Article
- Clinical Case of Respiratory Eucoleosis in a Dog from Bosnia and Herzegovina.Acta parasitologica · 2019Article
- Single and mixed feline lungworm infections: clinical, radiographic and therapeutic features of 26 cases (2013-2015).Journal of feline medicine and surgery · 2017Article
- Diagnosis and management of lungworm infections in cats: Cornerstones, dilemmas and new avenues.Journal of feline medicine and surgery · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Capillaria aerophila is a globally distributed parasite of the respiratory system of carnivores and can be considered the second most common lungworm after Aelurostrongylus abstrusus in domestic cats in the northern hemisphere. To evaluate the efficacy of Broadline (Merial), a combination of fipronil 8.3% w/v, (S)-methoprene 10% w/v, eprinomectin 0.4% w/v and praziquantel 8.3% w/v against C. aerophila, a controlled study with 20 naturally infected cats was conducted. Following blocking by body weight, cats were allocated randomly to two groups of ten animals each: control (untreated) or treated once with Broadline according to the label instructions. For evaluation of efficacy, faeces were examined for capillarid egg shedding prior to and weekly for 3 weeks after treatment, when the cats were necropsied for C. aerophila recovery. Following single topical administration of Broadline, faecal capillarid egg counts were significantly reduced by 93.5 to 99.1% (p < 0.01) compared to the controls. Cats treated harboured significantly fewer C. aerophila lungworms compared to the untreated controls (efficacy 82.4%, p = 0.016). Results of this study demonstrate that Capillaria lungworm burdens can be markedly reduced and that faecal egg shedding can be substantially lowered or eliminated following a single treatment with Broadline.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.