ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2015
Moderators of the effects of group-based physical exercise on cancer survivors' quality of life.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Physical activity interventions for disease-related physical and mental health during and following treatment in people with non-advanced colorectal cancer.The Cochrane database of systematic reviews · 2020Pooled it
- Targeting Exercise Interventions to Patients With Cancer in Need: An Individual Patient Data Meta-Analysis.Journal of the National Cancer Institute · 2018Pooled it
- Interventions for promoting habitual exercise in people living with and beyond cancer.The Cochrane database of systematic reviews · 2018Pooled it
- Understanding the Effects of Cancer-Related Factors on the Association Between Physical Activity and Quality of Life in Breast Cancer Survivors.Journal of physical activity & health · 2026Trial
- Trial
- Examining sociodemographic and health-related characteristics as moderators of an mHealth intervention on physical activity outcomes in young adult cancer survivors.Journal of cancer survivorship : research and practice · 2025Trial
- Moderators of physical activity and quality of life response to a physical activity intervention for breast cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Trial
- Relaxation versus exercise for improved quality of life in lymphoma survivors-a randomised controlled trial.Journal of cancer survivorship : research and practice · 2021Trial
- The impact of time after radiation treatment on dysphagia in patients with head and neck cancer enrolled in a swallowing therapy program.Head & neck · 2019Trial
- Effects of a combined physical and psychosocial training for children with cancer: a randomized controlled trial.BMC cancer · 2018Trial
- Long-term effectiveness and moderators of a web-based tailored intervention for cancer survivors on social and emotional functioning, depression, and fatigue: randomized controlled trial.Journal of cancer survivorship : research and practice · 2017Trial
- Effects of a multicomponent physical activity behavior change intervention on breast cancer survivor health status outcomes in a randomized controlled trial.Breast cancer research and treatment · 2016Trial
- Understanding the Effects of Cancer-Related Factors on the Association Between Physical Activity, Self-Efficacy and Exercise Barriers Among Breast Cancer Survivors.Psycho-oncology · 2025Article
- Mechanisms, Mediators, and Moderators of the Effects of Exercise on Chemotherapy-Induced Peripheral Neuropathy.Cancers · 2022Review
- Exploring Moderators of the Effect of High vs. Low-to-Moderate Intensity Exercise on Cardiorespiratory Fitness During Breast Cancer Treatment - Analyses of a Subsample From the Phys-Can RCT.Frontiers in sports and active living · 2022Article
- Adherence to and satisfaction with low-intensity physical activity and supervised moderate-high intensity exercise during chemotherapy for breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Article
- Persistent Post-Mastectomy Pain: Risk Factors and Current Approaches to Treatment.The journal of pain · 2018Review
- Peer mentorship to promote physical activity among cancer survivors: effects on quality of life.Psycho-oncology · 2015Article
Corrections and comments
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Authors and funding
11 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study explored demographic, clinical, and psychological moderators of the effect of a group-based physical exercise intervention on global quality of life (QoL) among cancer survivors who completed treatment.
methodsCancer survivors were assigned to a 12-week physical exercise (n = 147) or a wait-list control group (n = 62). The main outcome measure was global QoL, assessed with the EORTC QLQ-C30 at baseline and 12 weeks later. Potential moderators were age, gender, education level, marital status, employment status, type of treatment, time since treatment, the presence of comorbidities, fatigue, general self-efficacy, depression, and anxiety. Linear regression analyses were used to test effect modification of the intervention by each moderator variable using interaction tests (p ≤ 0.10).
resultsThe physical exercise intervention effect on global QoL was larger for cancer survivors who received radiotherapy (β = 10.3, 95 % confidence interval (CI) = 4.4; 16.2) than for cancer survivors who did not receive radiotherapy (β = 1.8, 95 % CI = -5.9; 9.5, p interaction = 0.10), larger for cancer survivors who received a combination of chemoradiotherapy (β = 13.0, 95 % CI = 6.0; 20.1) than for those who did not receive this combination of treatments (β = 2.5, 95 % CI = -3.7; 8.7, p interaction = 0.02), and larger for cancer survivors with higher baseline levels of fatigue (β = 12.6, 95 % CI = 5.7; 19.6) than for those with lower levels (β = 2.4, 95 % CI = -3.9; 8.7, p interaction = 0.03). No other moderating effects were found.
conclusionsThis study suggests that cancer treatment modality and baseline fatigue levels moderate the effect of a physical exercise program on cancer survivors'global QoL.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.