ArticleEuropean radiology2015
Low-dose CT screening in an Asian population with diverse risk for lung cancer: A retrospective cohort study.
Article in European radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Pooled it
- Hallmarks of lung cancer driven by inhalable particulate matter: From cell-intrinsic oncogenic traits to microenvironment remodeling.Innovation (Cambridge (Mass.)) · 2026Review
- Inter-observer consistency on subsolid nodule follow-up recommendation based on National Comprehensive Cancer Network (NCCN) guidelines in low-dose computed tomography (LDCT) lung cancer screening.Quantitative imaging in medicine and surgery · 2024Article
- Race, age at diagnosis and histological characteristics of lung cancer in never-smokers (LCINS) and ever-smokers in low-dose computed tomography (LDCT) screening: a systematic review and meta-analysis.Translational lung cancer research · 2024Article
- Lung Cancer Screening in Brazil Comparing the 2013 and 2021 USPSTF Guidelines.JAMA network open · 2023Article
- Low-dose computed tomography for lung cancer screening in Anhui, China: A randomized controlled trial.Frontiers in oncology · 2022Article
- Interobserver variability in Lung CT Screening Reporting and Data System categorisation in subsolid nodule-enriched lung cancer screening CTs.European radiology · 2021Article
- Landscape on CT screening for lung cancer in Asia.Lung Cancer (Auckland, N.Z.) · 2019Review
- Lung Cancer Screening with Low-Dose CT in Female Never Smokers: Retrospective Cohort Study with Long-term National Data Follow-up.Cancer research and treatment · 2018Article
- Screen-detected multiple primary lung cancers in the ITALUNG trial.Journal of thoracic disease · 2018Article
- Propensity score analysis of lung cancer risk in a population with high prevalence of non-smoking related lung cancer.BMC pulmonary medicine · 2017Article
- Patient factors to consider before lung cancer screening.Journal of thoracic disease · 2016Article
- Lung cancer screening using low dose CT: screening population and positive results definition.Journal of thoracic disease · 2015Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the performance of low-dose CT (LDCT) screening for lung cancer (LCA) detection in an Asian population with diverse risks for LCA. MATERIALS AND
methodsLCA screening was performed in 12,427 symptomless Asian subjects using either LDCT (5,771) or chest radiography (CXR) (6,656) in a non-trial setting. Subjects were divided into high-risk and non-high-risk groups. Data were collected on the number of patients with screening-detected LCAs and their survival in order to compare outcomes between LDCT and CXR screening with the stratification of risks considering age, sex and smoking status.
resultsIn the non-high-risk group, a significant difference was observed for the detection of lung cancer (adjusted OR, 5.07; 95 % CI, 2.72-9.45) and survival (adjusted HR of LCA survival between LDCT vs. CXR group, 0.08; 95 % CI, 0.01-0.62). No difference in detection or survival of LCA was noticed in the high-risk group. LCAs in the non-high-risk group were predominantly adenocarcinomas (96 %), and more likely to be part-solid or non-solid compared with those in the high-risk group (p = 0.023).
conclusionsIn the non-high-risk group, LDCT helps detect more LCAs and offers better survival than CXR screening, due to better detection of part solid or non-solid lung adenocarcinomas. KEY POINTS: • In an Asian non-high-risk group, LDCT helps detect more early-staged LCAs. • CT-detected lung cancers in non-high-risk subjects demonstrate better survival than CXR-detected cancers. • CT-detected lung cancers in non-high-risk subjects are predominantly part-solid or non-solid adenocarcinomas. • Mortality benefit of LDCT screening in non-high-risk subjects needs to be investigated.
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