Trial reportClinical oral investigations2015
Inter- and intra-test agreement of three commercially available molecular diagnostic tests for the identification of periodontal pathogens.
Trial report in Clinical oral investigations, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- A retrospective study on the impact of different antibiotic regimens in non-surgical periodontal therapy on microbial loads and therapy outcomes.Frontiers in oral health · 2025Article
- The Relationship between Dietary Habits and Periodontal Pathogens in a Sample of Romanian Children and Adolescents: A Cross-Sectional Study.Children (Basel, Switzerland) · 2023Article
- Influence of Anti-Infective Periodontal Therapy on Subgingival Microbiota Evaluated by Chair-Side Test Compared to qPCR-A Clinical Follow-Up Study.Antibiotics (Basel, Switzerland) · 2022Article
- Comparison of three qPCR-based commercial tests for detection of periodontal pathogens.Scientific reports · 2021Article
- Association of time under immunosuppression and different immunosuppressive medication on periodontal parameters and selected bacteria of patients after solid organ transplantation.Medicina oral, patologia oral y cirugia bucal · 2018Observational
- Periodontal condition is associated with disease duration and motoric disabilities in patients with ankylosing spondylitis: results of a cross-sectional study.Rheumatology international · 2018Article
- Dental and periodontal health, and microbiological and salivary conditions in patients with or without diabetes undergoing haemodialysis.International dental journal · 2017Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of the study was to compare the agreement and reproducibility of three test kits (IAI Pado Test 4⋅5®, micro-IDent®, and Carpegen® Perio Diagnostik) regarding the detection of Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, and Aggregatibacter actinomycetemcomitans. MATERIALS AND
methodsPeriodontal plaque samples from 20 patients suffering from severe chronic or aggressive periodontitis were split into two identical batches. Samples of batch 1 were evaluated immediately. Samples of batch 2 were analyzed after a storage period of 2 weeks at 4 °C.
resultsThe conformity of results obtained by the evaluated test kits as well as the concordant detection rate of periodontopathogens proved to be low. The agreement of the detection rate depends on the chosen test kit. The intra-test reproducibility of the qualitative analysis of identical plaque samples was perfect only for Carpegen® Perio Diagnostik. The quantitative analysis of the results expressed as n-fold difference of the test results revealed an only poor inter-test agreement between the test systems.
conclusionsResults of test kits for the identification of periodontopathogens are significantly influenced by the detection technology applied. The most advanced technology tended to give the most reliable results. CLINICAL RELEVANCE: As microbiological test results are supposed to be used for the planning of subsequent treatment strategies, clinicians should be aware of the limitations of results obtained by the different test systems and should use the results only in conjunction with clinical data for subsequent therapeutic decisions.
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