Evidence map›Paper›PMID 25680671›Full record

ReviewGastroenterology2015

Diet and upper gastrointestinal malignancies.

Christian C Abnet, Douglas A Corley, Neal D Freedman, Farin Kamangar

Open access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 6 pooled it
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 6 syntheses or guidelines pooled it, 110 citations in OpenAlex.

  1. Pooled it
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  17. Mapping the global research landscape on nutritional support for patients with gastrointestinal malignancy: visualization analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Christian C AbnetNutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland. Electronic address: abnetc@mail.nih.gov.
Douglas A CorleyDivision of Research, Kaiser Permanente of Northern California, Oakland, California.
Neal D FreedmanNutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland.
Farin KamangarDepartment of Public Health Analysis, School of Community Health and Policy, Morgan State University, Baltimore, Maryland; Digestive Oncology Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Division of Cancer Epidemiology and GeneticsKaiser Permanente · USMorgan State University · US

Funding

Upper Gastrointestinal Cancer StudiesZIACP000185 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI ABNET, CHRISTIAN · 2009 to 2025
$25.6M
Optimizing the use of colonoscopy for CRC screening in a large community-basedU54CA163262 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI CORLEY, DOUGLAS ALLEN, DOUBENI, CHYKE ABADAMA · 2011 to 2017
$9.6M
Intramural NIH HHS Z99 CA999999NCI NIH HHS U54 CA163262NCI NIH HHS U54CA163262
6 · The paper itself

Abstract

Diet is believed to modulate cancer risk and this relationship has been widely studied in the gastrointestinal tract. Observational epidemiologic studies have provided most of the evidence about the effects of diet on cancer risk because clinical trials to determine nutritional exposures are often impossible, impractical, or unaffordable. Although a few foods or nutrients are thought to protect against specific types of cancer, it seems clear that the strength and even direction of dietary associations (increasing or decreasing risk) is organ-site- and even histology-specific, along the gastrointestinal tract. Although some hypotheses are supported by a substantial body of observational data (drinking hot maté [an infusion of the herb Ilex Paraguarensis] contributes to esophageal cancer), there are not much data to support others. We discuss some highly touted hypotheses and draw interim conclusions about what is known and what could be done to improve the level of evidence. The complex nature of diet and its associations can be productively investigated with disease-specific studies. However, public health recommendations for normal-risk individuals regarding diet and gastrointestinal cancer should probably emphasize the importance of eating for overall health rather than eating specific foods to reduce risk for specific cancers.

Indexed as

DietRisk Reduction BehaviorAlcohol DrinkingAnimalsAnticarcinogenic AgentsAntioxidantsCoffeeEsophageal NeoplasmsFeeding BehaviorFood HandlingFruitHumansLife StyleMeatProtective FactorsRisk AssessmentAnticarcinogenic AgentsAntioxidantsCoffeeSodium Chloride, DietaryTeaVitaminsCancerEpidemiologyEsophagealGastric

Identifiers

PMID25680671
PMCPMC4414068
OpenAlexW2035577212

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.