Evidence map›Paper›PMID 25680654›Full record

ArticleChild abuse & neglect2015

Childhood trauma, PTSD, and problematic alcohol and substance use in low-income, African-American men and women.

Dorthie Cross, Thomas Crow, Abigail Powers, Bekh Bradley

Abstract read
In one paragraph

Article in Child abuse & neglect, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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  19. Alcohol consumption, interpersonal trauma, and drinking to cope with trauma-related distress: An auto-regressive, cross-lagged model.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dorthie CrossDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, USA.
Thomas CrowDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, USA.
Abigail PowersDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, USA.
Bekh BradleyAtlanta VA Medical Center, USA; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, USA.

Funding

Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
Genetic and Trauma-Related Risk Factors for PTSDR01MH071537 · NIMH · EMORY UNIVERSITY · PI RESSLER, KERRY J. · 2005 to 2014
$8.5M
RESEARCH TRAINING-PSYCHOBIOLOGICAL SCIENCEST32MH018264 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI MYERS, MICHAEL MORGAN · 1985 to 2012
$3.4M
Mechanisms of Intergenerational Impact of Maternal TraumaR01HD071982 · NICHD · EMORY UNIVERSITY · PI BRADLEY, BEKH · 2013 to 2017
$2.1M
Genetic and Trauma-Related Risk Factors for PTSD: From GWAS to FunctionR56MH071537 · NIMH · EMORY UNIVERSITY · PI RESSLER, KERRY J. · 2015 to 2015
$148k
The role of emotion dysregulation in PTSD symptomologyF32MH102890 · NIMH · EMORY UNIVERSITY · PI LOTT, ABIGAIL POWERS · 2014 to 2015
$102k
Howard Hughes Medical InstituteNCATS NIH HHS UL1 TR000454NCATS NIH HHS UL1TR000454.NICHD NIH HHS R01 HD071982NIMH NIH HHS F32 MH102890NIMH NIH HHS MH018264NIMH NIH HHS MH071537NIMH NIH HHS R01 MH071537NIMH NIH HHS R56 MH071537NIMH NIH HHS T32 MH018264
6 · The paper itself

Abstract

Previous studies demonstrate that PTSD mediates the relationship between childhood trauma and alcohol and substance use disorders and that PTSD and alcohol/substance use comorbidity is greater in men than in women. We sought to replicate and extend these findings in a predominantly low-income, African-American sample recruited from a public hospital. We administered measures of childhood trauma, PTSD symptoms, problematic alcohol use, and problematic substance use to 803 men and 2084 women. We examined rates of comorbidity in men and women. Next, two bootstrap analyses were used to test whether PTSD is a mediator between childhood trauma and problematic alcohol use and between childhood trauma and problematic substance use. Finally, two bootstrap analyses were used to test whether gender would moderate the indirect effect of PTSD in both the alcohol and substance use models. Results showed that although men and women reported similar overall PTSD symptom frequency, men were more likely than women to report PTSD comorbid with alcohol and/or substance use problems. In addition, PTSD partially mediated the relationship between childhood trauma and problematic alcohol use and between childhood trauma and problematic substance use. The indirect effects of PTSD on the relationship between childhood trauma and problematic alcohol use and between childhood trauma and problematic substance use were greater in men. This study demonstrates the important interplay of gender, childhood trauma, PTSD, and alcohol and substance use. Mental health providers should consider childhood trauma histories and diagnostic comorbidities when treatment planning.

Indexed as

AdultAdult Survivors of Child Adverse EventsAlcohol DrinkingBlack or African AmericanChildChild AbuseFemaleGeorgiaHumansMalePovertySex DistributionStress Disorders, Post-TraumaticSubstance-Related DisordersAlcoholChildhood traumaGenderPosttraumatic stress disorderSubstance

Identifiers

PMID25680654
PMCPMC4461539

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.