ReviewNeurosurgical review2015
Analgesic therapy for major spine surgery.
Review in Neurosurgical review, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06843174 (Perioperative Rectal Methadone in Spine Surgery), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Perioperative Rectal Methadone in Spine Surgery
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Efficacy of erector spinae plane block for postoperative analgesia lumbar surgery: a systematic review and meta-analysis.BMC anesthesiology · 2023Pooled it
- Efficacy and safety of liposomal bupivacaine versus bupivacaine for retrolaminar block for postoperative analgesia in patients undergoing posterior lumbar interbody fusion: a randomized controlled trial.BMC anesthesiology · 2026Trial
- A randomized clinical trial of erector spinae plane block and chronic pain after posterior lumbar surgery.Scientific reports · 2025Trial
- Analgesic efficacy of intravenous nefopam after spine surgery: a randomized, double-blind, placebo-controlled trial.F1000Research · 2020Trial
- Preemptive analgesia after lumbar spine surgery by pregabalin and celecoxib: a prospective study.Drug design, development and therapy · 2019Trial
- Prospective Preference Assessment of Potential Participants in the Perioperative Rectal Methadone in Spine Surgery (PROMISE) Trial.Canadian journal of pain = Revue canadienne de la douleur · 2026Article
- Effect of Surgeon-Performed Thoracic Paravertebral Block on Postoperative Pain in Adolescent Idiopathic Scoliosis Surgery: A Prospective Randomized Controlled Trial.Journal of personalized medicine · 2024Article
- Efficacy and safety of perioperative use of non-steroidal anti-inflammatory drugs for preemptive analgesia in lumbar spine surgery: a systematic review and meta-analysis.Perioperative medicine (London, England) · 2023Review
- Efficacy and Safety of Erector Spinae Plane Block for Perioperative Pain Management in Lumbar Spinal Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of pain research · 2023Review
- Is Opioid-free Anesthesia Possible by Using Erector Spinae Plane Block in Spinal Surgery?Cureus · 2021Article
- Multimodal Analgesia (MMA) Versus Patient-Controlled Analgesia (PCA) for One or Two-Level Posterior Lumbar Fusion Surgery.Journal of clinical medicine · 2020Article
- Bilateral Erector Spinae Plane Blocks for Open Posterior Lumbar Surgery.Journal of pain research · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pain following spine surgery is often difficult to control and can persist. Reduction of this pain requires a multidisciplinary approach that depends on contributions of both surgeons and anesthesiologists. The spine surgeon's role involves limiting manipulation of structures contributing to pain sensation in the spine, which requires an in-depth understanding of the specific anatomic etiologies of pain originating along the spinal axis. Anesthesiologists, on the other hand, must focus on preemptive, multimodal analgesic treatment regimens. In this review, we first discuss anatomic sources of pain within the spine, before delving into a specific literature-supported pain management protocol intended for use with spinal surgery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.