ArticleMarine biotechnology (New York, N.Y.)2015
Transcriptome analysis of shell color-related genes in the clam Meretrix meretrix.
Article in Marine biotechnology (New York, N.Y.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 76 citations in OpenAlex.
- Comparative Transcriptomics Reveal Key Genes and Pathways Driving the Diversity of Heritable Inner Shell Nacre Colors in the Freshwater Pearl Mussel (International journal of molecular sciences · 2025Article
- Research progress on formation mechanism of pearl.Heliyon · 2024Article
- Evolution and Function of the Notch Signaling Pathway: An Invertebrate Perspective.International journal of molecular sciences · 2024Review
- Identifying genes associated with genetic control of color polymorphism in the pearl oysterEvolutionary applications · 2023Article
- Stage-Specific Transcriptomes of the MusselGenes · 2023Article
- Article
- The mud-dwelling clamProceedings of the National Academy of Sciences of the United States of America · 2022Article
- MiRNA-mRNA Integration Analysis Reveals the Regulatory Roles of MiRNAs in Shell Pigmentation of the Manila clam (Ruditapes philippinarum).Marine biotechnology (New York, N.Y.) · 2021Article
- Article
- Identification of Functional SSR Markers in Freshwater Ornamental Shrimps Neocaridina denticulata Using Transcriptome Sequencing.Marine biotechnology (New York, N.Y.) · 2020Article
- Integrated analysis of microRNA and mRNA expression profiles in Crassostrea gigas to reveal functional miRNA and miRNA-targets regulating shell pigmentation.Scientific reports · 2020Article
- Tracing key genes associated with the Pinctada margaritifera albino phenotype from juvenile to cultured pearl harvest stages using multiple whole transcriptome sequencing.BMC genomics · 2020Article
- Article
- Histological and Expression Differences Among Different Mantle Regions of the Yesso Scallop (Patinopecten yessoensis) Provide Insights into the Molecular Mechanisms of Biomineralization and Pigmentation.Marine biotechnology (New York, N.Y.) · 2019Article
- Clam Genome Sequence Clarifies the Molecular Basis of Its Benthic Adaptation and Extraordinary Shell Color Diversity.iScience · 2019Article
- Comparative transcriptomic and proteomic analysis of yellow shell and black shell pearl oysters, Pinctada fucata martensii.BMC genomics · 2019Article
- Transcriptome profiling analysis reveals key genes of different coat color in sheep skin.PeerJ · 2019Article
- Comparison of Two Pearl Sacs Formed in the Same Recipient Oyster with Different Genetic Background Involved in Yellow Pigmentation in Pinctada fucata.Marine biotechnology (New York, N.Y.) · 2018Article
- Integrated transcriptomic and proteomic analyses reveal potential mechanisms linking thermal stress and depressed disease resistance in the turbot Scophthalmus maximus.Scientific reports · 2018Article
- Transcriptional profiling of long non-coding RNAs in mantle of Crassostrea gigas and their association with shell pigmentation.Scientific reports · 2018Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Color polymorphism has received much attention due to its strong implications for speciation and adaptation. In contrast to body color, little is currently known about the molecular mechanism of shell color formation. This study represents the first analysis of the relationship between whole-scale gene expression and shell color variations in the marine bivalve mollusks via comparative transcriptome analyses. Three clam Meretrix meretrix strains with different and monotonous shell color patterns, which were developed by our 10-year artificial selection, combined with clams with nearly white shell color were used in the analyses. The results supported the idea that there was a relationship between gene expression and shell pigmentation in the clam M. meretrix, and complex signal transduction were involved. It was proposed that Notch signaling pathway played a crucial role in shell pigmentation in a gene-dosage dependent pattern and also potentially involved in the shell color patterning. Calcium signaling process may equally be implicated in shell color formation via activation of Notch pathway. Other differentially expressed genes (e.g., Myl, Mitf) potentially implicated in shell color pigmentation were also noticed. This study provides information on the expression profiles of clams with different shell color morphs and sheds light on color formation mechanism of shell.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.