ArticlePloS one2015
Transoceanic spreading of pathogenic strains of Vibrio parahaemolyticus with distinctive genetic signatures in the recA gene.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 37 citations in OpenAlex.
- Antimicrobial resistance ofApplied and environmental microbiology · 2025Article
- EpibioticPeerJ · 2025Article
- Vibrio parahaemolyticus Epidemiology and Pathogenesis: Novel Insights on an Emerging Foodborne Pathogen.Advances in experimental medicine and biology · 2023Article
- Multilocus Sequence Typing and Virulence Potential ofMicrobiology spectrum · 2022Article
- Phylogenetic and Biogeographic Patterns of Vibrio parahaemolyticus Strains from North America Inferred from Whole-Genome Sequence Data.Applied and environmental microbiology · 2021Article
- Virulence, Antimicrobial Susceptibility, Molecular and Epidemiological Characteristics of a New Serotype ofFrontiers in microbiology · 2020Article
- Clustering ofFrontiers in public health · 2019Article
- Article
- Genetic and population analyses of Vibrio parahaemolyticus isolates from three major coastal regions in China.Future microbiology · 2018Article
- Phylogeographic patterns in the Philippine archipelago influence symbiont diversity in the bobtail squidEcology and evolution · 2018Article
- Genomic Variation and Evolution ofmBio · 2017Article
- Parallel Evolution of Two Clades of an Atlantic-Endemic Pathogenic Lineage of Vibrio parahaemolyticus by Independent Acquisition of Related Pathogenicity Islands.Applied and environmental microbiology · 2017Article
- Defining a Core Genome Multilocus Sequence Typing Scheme for the Global Epidemiology of Vibrio parahaemolyticus.Journal of clinical microbiology · 2017Article
- Outbreak of Vibrio parahaemolyticus Sequence Type 120, Peru, 2009.Emerging infectious diseases · 2016Article
- A Nonautochthonous U.S. Strain of Vibrio parahaemolyticus Isolated from Chesapeake Bay Oysters Caused the Outbreak in Maryland in 2010.Applied and environmental microbiology · 2016Article
- Is El Niño a long-distance corridor for waterborne disease?Nature microbiology · 2016Article
- Examination of clinical and environmental Vibrio parahaemolyticus isolates by multi-locus sequence typing (MLST) and multiple-locus variable-number tandem-repeat analysis (MLVA).Frontiers in microbiology · 2015Article
- Characterization of Vibrio parahaemolyticus clinical strains from Maryland (2012-2013) and comparisons to a locally and globally diverse V. parahaemolyticus strains by whole-genome sequence analysis.Frontiers in microbiology · 2015Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vibrio parahaemolyticus is an important human pathogen whose transmission is associated with the consumption of contaminated seafood. Consistent multilocus sequence typing for V. parahaemolyticus has shown difficulties in the amplification of the recA gene by PCR associated with a lack of amplification or a larger PCR product than expected. In one strain (090-96, Peru, 1996), the produced PCR product was determined to be composed of two recA fragments derived from different Vibrio species. To better understand this phenomenon, we sequenced the whole genome of this strain. The hybrid recA gene was found to be the result of a fragmentation of the original lineage-specific recA gene resulting from a DNA insertion of approximately 30 kb in length. This insert had a G+C content of 38.8%, lower than that of the average G+C content of V. parahaemolyticus (45.2%), and contained 19 ORFs, including a complete recA gene. This new acquired recA gene deviated 24% in sequence from the original recA and was distantly related to recA genes from bacteria of the Vibrionaceae family. The reconstruction of the original recA gene (recA3) identified the precursor as belonging to ST189, a sequence type reported previously only in Asian countries. The identification of this singular genetic feature in strains from Asia reveals new evidence for genetic connectivity between V. parahaemolyticus populations at both sides of the Pacific Ocean that, in addition to the previously described pandemic clone, supports the existence of a recurrent transoceanic spreading of pathogenic V. parahaemolyticus with the corresponding potential risk of pandemic expansion.
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