Evidence map›Paper›PMID 25679378›Full record

ArticlePloS one2015

Neck circumference, along with other anthropometric indices, has an independent and additional contribution in predicting fatty liver disease.

Bi-xia Huang, Ming-fan Zhu, Ting Wu, Jing-ya Zhou, Yan Liu, Xiao-lin Chen, Rui-fen Zhou, Li-Jun Wang, Yu-ming Chen, Hui-lian Zhu

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 67 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Bi-xia HuangFaculty of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong Province, The People's Republic of China.
Ming-fan ZhuHealth Examination Centre, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, The People's Republic of China.
Ting WuFaculty of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong Province, The People's Republic of China.
Jing-ya ZhouFaculty of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong Province, The People's Republic of China.
Yan LiuFaculty of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong Province, The People's Republic of China.
Xiao-lin ChenFaculty of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong Province, The People's Republic of China.
Rui-fen ZhouFaculty of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong Province, The People's Republic of China.
Li-Jun WangFaculty of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong Province, The People's Republic of China.
Yu-ming ChenFaculty of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong Province, The People's Republic of China.
Hui-lian ZhuFaculty of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong Province, The People's Republic of China.
Sun Yat-sen University · CNThe First Affiliated Hospital, Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimPrevious studies have indicated that neck circumference is a valuable predictor for obesity and metabolic syndrome, but little evidence is available for fatty liver disease. We examined the association of neck circumference with fatty liver disease and evaluated its predictive value in Chinese adults.

methodsThis cross-sectional study comprised 4053 participants (1617 women and 2436 men, aged 20-88) recruited from the Health Examination Center in Guangzhou, China between May 2009 and April 2010. Anthropometric measurements were taken, abdominal ultrasonography was conducted and blood biochemical parameters were measured. Covariance, logistic regression and receiver operating characteristic curve analyses were employed.

resultsThe mean neck circumference was greater in subjects with fatty liver disease than those without the disease in both women and men after adjusting for age (P<0.001). Logistic regression analysis showed that the age-adjusted ORs (95% CI) of fatty liver disease for quartile 4 (vs. quartile 1) of neck circumference were 7.70 (4.95-11.99) for women and 12.42 (9.22-16.74) for men. After further adjusting for other anthropometric indices, both individually and combined, the corresponding ORs remained significant (all P-trends<0.05) but were attenuated to 1.94-2.53 for women and 1.45-2.08 for men. An additive interaction existed between neck circumference and the other anthropometric measures (all P<0.05). A high neck circumference value was associated with a much greater prevalence of fatty liver disease in participants with both high and normal BMI, waist circumference and waist-to-hip ratio values.

conclusionsNeck circumference was an independent predictor for fatty liver disease and provided an additional contribution when applied with other anthropometric measures.

Indexed as

Body Weights and MeasuresNeckAdultChinaCross-Sectional StudiesFatty LiverFemaleHumansMaleMiddle AgedOdds RatioPrognosisRisk FactorsROC Curve

Identifiers

PMID25679378
PMCPMC4334519
OpenAlexW2063234392

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.