Evidence map›Paper›PMID 25679229›Full record

ReviewNutrients2015

Review: The potential of the common bean (Phaseolus vulgaris) as a vehicle for iron biofortification.

Nicolai Petry, Erick Boy, James P Wirth, Richard F Hurrell

Abstract readReview
In one paragraph

Review in Nutrients, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Expression analysis of phosphatase III-B subfamily in common bean reveals two storage proteins highly expressed during seed formation and germination.Physiology and molecular biology of plants : an international journal of functional plant biology · 2026
    Article
  5. Article
  6. Molecular Breeding for Fungal Resistance in Common Bean.International journal of molecular sciences · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Genetic Diversity of Common Bean (Plants (Basel, Switzerland) · 2024
    Article
  11. Article
  12. Article
  13. Review
  14. Characterization ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2023
    Article
  15. Article
  16. Article
  17. Biofortification of common bean (Food and energy security · 2023
    Review
  18. Article
  19. Article
  20. Article

24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nicolai PetryGroundwork LLC, Crans-près-Céligny 1299 Switzerland. nico@groundworkhealth.org.
Erick BoyInternational Food Policy Research Institute, Washington, DC 20006-1002, USA. E.Boy@cgiar.org.
James P WirthGroundwork LLC, Crans-près-Céligny 1299 Switzerland. james@groundworkhealth.org.
Richard F HurrellInstitute of Food, Nutrition and Health, Laboratory of Human Nutrition, ETH Zurich, 8092 Zurich, Switzerland. richard.hurrell@hest.ethz.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Common beans are a staple food and the major source of iron for populations in Eastern Africa and Latin America. Bean iron concentration is high and can be further increased by biofortification. A major constraint to bean iron biofortification is low iron absorption, attributed to inhibitory compounds such as phytic acid (PA) and polyphenol(s) (PP). We have evaluated the usefulness of the common bean as a vehicle for iron biofortification. High iron concentrations and wide genetic variability have enabled plant breeders to develop high iron bean varieties (up to 10 mg/100 g). PA concentrations in beans are high and tend to increase with iron biofortification. Short-term human isotope studies indicate that iron absorption from beans is low, PA is the major inhibitor, and bean PP play a minor role. Multiple composite meal studies indicate that decreasing the PA level in the biofortified varieties substantially increases iron absorption. Fractional iron absorption from composite meals was 4%-7% in iron deficient women; thus the consumption of 100 g biofortified beans/day would provide about 30%-50% of their daily iron requirement. Beans are a good vehicle for iron biofortification, and regular high consumption would be expected to help combat iron deficiency (ID).

Indexed as

Biological AvailabilityFood, FortifiedAdultFemaleHumansIntestinal AbsorptionIron, DietaryIron IsotopesMalePhytic AcidPolyphenolsSeedsIron, DietaryIron IsotopesPhytic AcidPolyphenols

Identifiers

PMID25679229
PMCPMC4344581

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.