Trial reportPloS one2015
Effectiveness of an Internet intervention for family caregivers of people with dementia: results of a randomized controlled trial.
Trial report in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 17 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
88 citing papers in PubMed, 17 syntheses or guidelines pooled it, 224 citations in OpenAlex.
- Completeness of Telehealth Interventions Reporting in Randomized Controlled Trials for Caregivers of People With Dementia: Systematic Review.Journal of medical Internet research · 2025Pooled it
- A systematic review of the effectiveness of technological interventions for caregivers of people with dementia: effects on quality of life and psychoemotional variables.Frontiers in public health · 2025Pooled it
- What's behind the Dashboard? Intervention Mapping of a Mobility Outcomes Monitoring System for Rehabilitation.International journal of environmental research and public health · 2022Pooled it
- The Effectiveness of Multi-Component Interventions on the Positive and Negative Aspects of Well-Being among Informal Caregivers of People with Dementia: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Non-pharmacological Interventions for Caregivers with Depression and Caregivers of Care Recipients with Co-morbid Depression: Systematic Review and Meta-analysis.Journal of general internal medicine · 2021Pooled it
- The Effectiveness of e-Health Solutions for Aging With Cognitive Impairment: A Systematic Review.The Gerontologist · 2021Pooled it
- Psychosocial interventions to support the mental health of informal caregivers of persons living with dementia - a systematic literature review.BMC geriatrics · 2021Pooled it
- Remotely delivered information, training and support for informal caregivers of people with dementia.The Cochrane database of systematic reviews · 2021Pooled it
- Tele-Health Intervention for Carers of Dementia Patients-A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Frontiers in aging neuroscience · 2021Pooled it
- Retracted: Internet-Based Supportive Interventions for Family Caregivers of People With Dementia: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2020Pooled it
- Internet-Based Interventions for Carers of Individuals With Psychiatric Disorders, Neurological Disorders, or Brain Injuries: Systematic Review.Journal of medical Internet research · 2019Pooled it
- Web-Based Interventions to Improve Mental Health in Home Caregivers of People With Dementia: Meta-Analysis.Journal of medical Internet research · 2019Pooled it
- Acceptability of psychosocial interventions for dementia caregivers: a systematic review.BMC psychiatry · 2019Pooled it
- Impact of Internet-Based Interventions on Caregiver Mental Health: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2018Pooled it
- Internet-Based Interventions Aimed at Supporting Family Caregivers of People With Dementia: Systematic Review.Journal of medical Internet research · 2018Pooled it
- Computer and telephone delivered interventions to support caregivers of people with dementia: a systematic review of research output and quality.BMC geriatrics · 2017Pooled it
- Components and Outcomes of Internet-Based Interventions for Caregivers of Older Adults: Systematic Review.Journal of medical Internet research · 2017Pooled it
- Digital Peer Support Intervention for Family Caregivers of Individuals With Neuromuscular Disease: Randomized Controlled Trial.Journal of medical Internet research · 2026Trial
- Problem-solving training to improve caregiver burden and depressive symptoms among dementia caregivers: personal and clinical factors of responders vs. non-responders.Frontiers in public health · 2025Trial
- Results of a Randomized Trial Testing the Efficacy of Tele-Savvy, an Online Synchronous/Asynchronous Psychoeducation Program for Family Caregivers of Persons Living with Dementia.The Gerontologist · 2022Trial
28 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe World Health Organization stresses the importance of accessible and (cost)effective caregiver support, given the expected increase in the number of people with dementia and the detrimental impact on the mental health of family caregivers.
methodsThis study assessed the effectiveness of the Internet intervention 'Mastery over Dementia'. In a RCT, 251 caregivers, of whom six were lost at baseline, were randomly assigned to two groups. Caregivers in the experimental group (N = 149) were compared to caregivers who received a minimal intervention consisting of e-bulletins (N = 96). Outcomes were symptoms of depression (Center for Epidemiologic Studies Depression Scale: CES-D) and anxiety (Hospital Anxiety and Depression Scale: HADS-A). All data were collected via the Internet, and an intention-to-treat analysis was carried out.
resultsAlmost all caregivers were spouses or children (in-law). They were predominantly female and lived with the care recipient in the same household. Age of the caregivers varied from 26 to 87 years. Level of education varied from primary school to university, with almost half of them holding a bachelor's degree or higher. Regression analyses showed that caregivers in the experimental group showed significantly lower symptoms of depression (p = .034) and anxiety (p = .007) post intervention after adjustment for baseline differences in the primary outcome scores and the functional status of the patients with dementia. Effect sizes were moderate for symptoms of anxiety (.48) and small for depressive symptoms (.26).
conclusionsThe Internet course 'Mastery over Dementia' offers an effective treatment for family caregivers of people with dementia reducing symptoms of depression and anxiety. The results of this study justify further development of Internet interventions for family caregivers of people with dementia and suggest that such interventions are promising for keeping support for family caregivers accessible and affordable. The findings are even more promising because future generations of family caregivers will be more familiar with the Internet.
trial registrationDutch Trial Register NTR-2051 www.trialregister.nl/trialreg/admin/rctview.asp?TC=2051.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.