Evidence map›Paper›PMID 25678986›Full record

ArticleCurrent environmental health reports2014

Zebrafish: A marvel of high-throughput biology for 21

Sean M Bugel, Robert L Tanguay, Antonio Planchart

Abstract read
In one paragraph

Article in Current environmental health reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed.

  1. Toxics · 2026
    Article
  2. Review
  3. Article
  4. Transient fetal hyperglycemia reprograms adipogenesis, lipogenesis, and insulin signaling in zebrafish.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Inhibition of Fin Regeneration in Fathead Minnow (Environmental science & technology · 2025
    Article
  12. Unravelling the developmental toxicity of heavy metals using zebrafish as a model: a narrative review.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sean M BugelDepartment of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR 97333.
Robert L TanguayDepartment of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR 97333.
Antonio PlanchartDepartment of Biological Sciences, North Carolina State University, Raleigh, NC 27695.

Funding

Reducing Susceptibility to Environmental Stress Throughout the Life SpanP30ES000210 · NIEHS · OREGON STATE UNIVERSITY · PI BECKMAN, JOSEPH S · 1985 to 2015
$21.4M
MODE OF ACTION OF ENVIRONMENTAL TOXICANTST32ES007060 · NIEHS · OREGON STATE UNIVERSITY · PI Jamie DeWitt, Siva Kumar Kolluri · 1985 to 2026
$11.6M
Defining nanomaterial-biological interactions to enhance biocompatibility and bioR01ES016896 · NIEHS · OREGON STATE UNIVERSITY · PI TANGUAY, ROBYN L · 2008 to 2012
$1.5M
NIEHS NIH HHS P30 ES000210NIEHS NIH HHS R01 ES016896NIEHS NIH HHS T32 ES007060
6 · The paper itself

Abstract

The evolutionary conservation of genomic, biochemical and developmental features between zebrafish and humans is gradually coming into focus with the end result that the zebrafish embryo model has emerged as a powerful tool for uncovering the effects of environmental exposures on a multitude of biological processes with direct relevance to human health. In this review, we highlight advances in automation, high-throughput (HT) screening, and analysis that leverage the power of the zebrafish embryo model for unparalleled advances in our understanding of how chemicals in our environment affect our health and wellbeing.

Indexed as

environmental exposurehigh-throughput screeninghuman healthZebrafish embryo model

Identifiers

PMID25678986
PMCPMC4321749

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.