Evidence map›Paper›PMID 25678940›Full record

ArticleThe journal of physical chemistry. C, Nanomaterials and interfaces2014

Rectification of Ion Current in Nanopores Depends on the Type of Monovalent Cations: Experiments and Modeling.

Trevor Gamble, Karl Decker, Timothy S Plett, Matthew Pevarnik, Jan-Frederik Pietschmann, Ivan Vlassiouk, Aleksei Aksimentiev, Zuzanna S Siwy

Abstract read
In one paragraph

Article in The journal of physical chemistry. C, Nanomaterials and interfaces, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Graphite-Based Bio-Mimetic Nanopores for Protein Sequencing and Beyond.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Nanoscale Ion Pump Derived from a Biological Water Channel.The journal of physical chemistry. B · 2017
    Article
  9. Modulation of Molecular Flux Using a Graphene Nanopore Capacitor.The journal of physical chemistry. B · 2017
    Article
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Trevor GambleDepartment of Physics and Astronomy, University of California, Irvine , Irvine, California 92697, United States.
Karl DeckerDepartment of Physics, Beckman Institute, University of Illinois , Urbana, Illinois 61820, United States.
Timothy S PlettDepartment of Physics and Astronomy, University of California, Irvine , Irvine, California 92697, United States.
Matthew PevarnikDepartment of Physics and Astronomy, University of California, Irvine , Irvine, California 92697, United States.
Jan-Frederik PietschmannNumerical Analysis and Scientific Computing, TU Darmstadt, Germany.
Ivan VlassioukOak Ridge National Laboratory, Oak Ridge, Tennessee 37831, United States.
Aleksei AksimentievDepartment of Physics, Beckman Institute, University of Illinois , Urbana, Illinois 61820, United States.
Zuzanna S SiwyDepartment of Physics and Astronomy, University of California, Irvine , Irvine, California 92697, United States ; Department of Chemistry and Department of Biomedical Engineering, University of California , Irvine, California 92697, United States ; Department of Chemistry and Department of Biomedical Engineering, University of California , Irvine, California 92697, United States.

Funding

Plasmonic nanopores for trapping, controlled motion and sequencing of DNAR01HG007406 · NHGRI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI AKSIMENTIEV, ALEKSEI · 2013 to 2016
$2.4M
NHGRI NIH HHS R01 HG007406
6 · The paper itself

Abstract

Rectifying nanopores feature ion currents that are higher for voltages of one polarity compared to the currents recorded for corresponding voltages of the opposite polarity. Rectification of nanopores has been found to depend on the pore opening diameter and distribution of surface charges on the pore walls as well as pore geometry. Very little is known, however, on the dependence of ionic rectification on the type of transported ions of the same charge. We performed experiments with single conically shaped nanopores in a polymer film and recorded current-voltage curves in three electrolytes: LiCl, NaCl, and KCl. Rectification degrees of the pores, quantified as the ratio of currents recorded for voltages of opposite polarities, were the highest for KCl and the lowest for LiCl. The experimental observations could not be explained by a continuum modeling based on the Poisson-Nernst-Planck equations. All-atom molecular dynamics simulations revealed differential binding between Li

Identifiers

PMID25678940
PMCPMC4317049

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.