Evidence map›Paper›PMID 25678936›Full record

ArticleLaser & photonics reviews2014

Talbot holographic illumination nonscanning (THIN) fluorescence microscopy.

Yuan Luo, Vijay Raj Singh, Dipanjan Bhattacharya, Elijah Y S Yew, Jui-Chang Tsai, Sung-Liang Yu, Hsi-Hsun Chen, Jau-Min Wong, Paul Matsudaira, Peter T C So and 1 more

Open access · greenAbstract read
In one paragraph

Article in Laser & photonics reviews, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

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  4. Biomedical optics express · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Yuan Luo *Center for Optoelectronic Biomedicine, College of Medicine, National Taiwan University, Taipei, 10051, Taiwan R.O.C.
Vijay Raj Singh *Singapore-MIT Alliance for Research and Technology (SMART) Centre, 1 CREATE Way, #10-01 CREATE Tower, 138602, Singapore.
Dipanjan Bhattacharya *Singapore-MIT Alliance for Research and Technology (SMART) Centre, 1 CREATE Way, #10-01 CREATE Tower, 138602, Singapore.
Elijah Y S Yew *Singapore-MIT Alliance for Research and Technology (SMART) Centre, 1 CREATE Way, #10-01 CREATE Tower, 138602, Singapore.
Jui-Chang TsaiCenter for Optoelectronic Biomedicine, College of Medicine, National Taiwan University, Taipei, 10051, Taiwan R.O.C.
Sung-Liang YuDepartment of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, 10055, Taiwan R.O.C.
Hsi-Hsun ChenCenter for Optoelectronic Biomedicine, College of Medicine, National Taiwan University, Taipei, 10051, Taiwan R.O.C.
Jau-Min WongDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, 10048, Taiwan, R.O.C.
Paul MatsudairaSingapore-MIT Alliance for Research and Technology (SMART) Centre, 1 CREATE Way, #10-01 CREATE Tower, 138602, Singapore.
Peter T C SoSingapore-MIT Alliance for Research and Technology (SMART) Centre, 1 CREATE Way, #10-01 CREATE Tower, 138602, Singapore.
George BarbastathisSingapore-MIT Alliance for Research and Technology (SMART) Centre, 1 CREATE Way, #10-01 CREATE Tower, 138602, Singapore.
National Taiwan University · TWMassachusetts Institute of Technology · USNational University of Singapore · SGSingapore-MIT Alliance for Research and Technology · SGNational Taiwan University Hospital · TW

Funding

Wide-Field Short-Wave Infrared (SWIR) multiphoton (MP) tissue imagingP41EB015871 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SO, PETER T. · 2012 to 2021
$11.3M
A Spatial-Spectral Volume Holographic Imaging System for Ex-Vivo and In-Vivo CancR01CA134424 · NCI · UNIVERSITY OF ARIZONA · PI KOSTUK, RAYMOND K · 2009 to 2013
$2.0M
NCI NIH HHS R01 CA134424NIBIB NIH HHS P41 EB015871
6 · The paper itself

Abstract

Optical sectioning techniques offer the ability to acquire three-dimensional information from various organ tissues by discriminating between the desired in-focus and out-of-focus (background) signals. Alternative techniques to confocal, such as active structured illumination, exist for fast optically sectioned images, but they require individual axial planes to be imaged consecutively. In this article, an imaging technique (THIN), by utilizing active Talbot illumination in 3D and multiplexed holographic Bragg filters for depth discrimination, is demonstrated for imaging in vivo 3D biopsy without mechanical or optical axial scanning.

Indexed as

3D wide field Microscopyholographic Bragg filtersoptical sectioningTalbot effect

Identifiers

PMID25678936
PMCPMC4321697
OpenAlexW1910925601

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.