ArticleJournal of geriatric cardiology : JGC2015
Characterization of lipid parameters in diabetic and non-diabetic atherosclerotic patients.
Article in Journal of geriatric cardiology : JGC, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 17 citations in OpenAlex.
- Prevalence of Dyslipidaemia among Type 2 Diabetes Mellitus Patients in the Western Cape, South Africa.International journal of environmental research and public health · 2020Article
- Lower circulating kisspeptin and primary hypogonadism in men with type 2 diabetes.Endocrinology, diabetes & metabolism · 2019Article
- The interaction of dyslipidaemia with glycaemia in an adult population study.Journal of diabetes and metabolic disorders · 2018Article
- Prevalence and pattern of dyslipidemia in Nepalese individuals with type 2 diabetes.BMC research notes · 2017Article
- Consumption of extra-virgin olive oil rich in phenolic compounds improves metabolic control in patients with type 2 diabetes mellitus: a possible involvement of reduced levels of circulating visfatin.Journal of endocrinological investigation · 2016Article
- Age- and sex-related changes in fasting plasma glucose and lipoprotein in cynomolgus monkeys.Lipids in health and disease · 2016Article
- Kidney stone characteristics in diabetics versus nondiabetics at a tertiary care center in Saudi Arabia.Urology annalsArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND &
objectiveThe relationship between lipid profile perturbation and diabetes associated complications has long been an area of interest. Dyslipidemia is a potent predictor of cardiovascular morbidity and mortality in diabetic patients. The aim of present study was to investigate relationship between aging and lipid profiles in diabetic and non-diabetic atherosclerotic patients.
methodsFive hundred and seventy six individuals (45-75 year age) participated in this study. Among these, 192 were having history of diabetes mellitus and atherosclerosis. Individuals are categorized on the base of health (normal, non-diabetic atherosclerosis, diabetic atherosclerosis) and age (45-55 years, 56-65 years, and 66-75 years). All the participants were subjected to the procedures like a detailed history, biochemical analysis for fasting blood sugar, hemoglobin A1c, total cholesterol (TC), triglycerides (TG), low-density lipoprotein-(LDL), very low-density lipoprotein (VLDL) and high-density lipoprotein (HDL). All these parameters were compared between diabetic and non-diabetic atherosclerotic patients of all three age groups. TC/HDL and LDL/HDL were also calculated.
resultsDiabetic atherosclerotic individuals (both males and females) had high level of TC, TG, LDL, VLDL and low level of HDL in comparison to non-diabetic atherosclerotic and normal control individuals. Among all three age groups, lipoprotein abnormality was observed to be more frequent in females than males. There was a significant increase in TC/HDL and LDL/HDL ratio in diabetic atherosclerotic subjects compared to age and sex matched non-diabetic atherosclerotic and normal control.
conclusionsDegree of dyslipidemia increases with increase in age in both genders. Female are more prone to diabetic dyslipidemia and hence have more risk of developing atherosclerosis with increasing age.
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