SynthesisDrug design, development and therapy2015
Steroid for epidural injection in spinal stenosis: a systematic review and meta-analysis.
Synthesis in Drug design, development and therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 15 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Activity Levels Amongst Elderly Patients With Symptomatic Lumbar Spinal Stenosis Before and After Decompressive Surgery
Postural Imbalance Amongst Elderly Patients With Symptomatic Lumbar Spinal Stenosis Before and After Decompressive Surgery
Who cites it
15 citing papers in PubMed, 4 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Effectiveness of epidural steroid injections in the treatment of lumbar radiculopathy: a systematic review and meta-analysis.Frontiers in pain research (Lausanne, Switzerland) · 2026Pooled it
- Non-operative treatment for lumbar spinal stenosis with neurogenic claudication: an updated systematic review.BMJ open · 2022Pooled it
- Management of lumbar spinal stenosis.BMJ (Clinical research ed.) · 2016Pooled it
- Epidural injections with or without steroids in managing chronic low back pain secondary to lumbar spinal stenosis: a meta-analysis of 13 randomized controlled trials.Drug design, development and therapy · 2015Pooled it
- Ultrasound-guided caudal epidural injection to treat symptoms of lumbar spinal stenosis: a retrospective study.European journal of translational myology · 2024Article
- Repeated epidural delivery of Shinbaro2: effects on neural recovery, inflammation, and pain modulation in a rat model of lumbar spinal stenosis.Frontiers in pharmacology · 2024Article
- Epidural Steroid Injections for Low Back Pain: A Narrative Review.International journal of environmental research and public health · 2021Review
- Conservative Treatment and Percutaneous Pain Relief Techniques in Patients with Lumbar Spinal Stenosis: WFNS Spine Committee Recommendations.World neurosurgery: X · 2020Article
- Short-Term Efficacy of Epidural Injection of Triamcinolone Through Translaminar Approach for the Treatment of Lumbar Canal Stenosis.Anesthesiology and pain medicine · 2020Article
- An Algorithmic Approach to Treating Lumbar Spinal Stenosis: An Evidenced-Based Approach.Pain medicine (Malden, Mass.) · 2019Review
- Article
- Current concepts and recent advances in understanding and managing lumbar spine stenosis.F1000Research · 2019Review
- Observational
- Steroid Administration is Effective to Prevent Strictures After Endoscopic Esophageal Submucosal Dissection: A Network Meta-Analysis.Medicine · 2015Review
- Comments on a systematic review and meta-analysis of steroids for epidural injections in spinal stenosis.Drug design, development and therapy · 2015Article
Corrections and comments
- Commented on by
- Commented on byAuthors' reply.2015
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate the effectiveness and safety of epidural steroid injections in patients with lumbar spinal stenosis (LSS).
methodsWe performed a search on the CENTRAL, Pubmed, Embase and Cochrane databases up to September 2014. We recovered 17 original articles, of which only 10 were in full compliance with the randomized controlled trial (RCT) criteria. These articles were reviewed in an independent and blinded way by two reviewers who were previously trained to extract data and score their quality by the criteria of the Cochrane Handbook (5.1.0).
resultsWe accepted ten studies with 1,010 participants. There is minimal evidence that shows that epidural steroid injections are better than lidocaine alone, regardless of the mode of epidural injection. There is a fair short-term and long-term benefit for treating spinal stenosis with local anesthetic and steroids.
conclusionsThis meta-analysis suggests that epidural steroid injections provide limited improvement in short-term and long-term benefits in LSS patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.