Evidence map›Paper›PMID 25678571›Full record

ReviewHuman reproduction (Oxford, England)2015

Emergency contraception. Widely available and effective but disappointing as a public health intervention: a review.

ESHRE CapriWorkshop Group

Registry-linked trialAbstract readReview
In one paragraph

Review in Human reproduction (Oxford, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03395756 (Investigation of the Potential for Intramuscular Depot Medroxyprogesterone Acetate as Emergency Contraception), which is not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03395756 early_phase1completednot on this mapstarted 2018, after this paper: background citation

Investigation of the Potential for Intramuscular Depot Medroxyprogesterone Acetate as Emergency Contraception

TypeinterventionalSponsorUniversity of Southern CaliforniaRan2018 to 2020Enrolled30ConditionsEmergency Contraception, ContraceptionArmsDepot-Medroxyprogestereone Acetate
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Interventions for emergency contraception.The Cochrane database of systematic reviews · 2019
    Pooled it
  2. Interventions for emergency contraception.The Cochrane database of systematic reviews · 2017
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Detection of ovulation, a review of currently available methods.Bioengineering & translational medicine · 2017
    Review
  15. Observational
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

ESHRE CapriWorkshop Group

Funding

Infrastructure for Population Research at PrincetonR24HD047879 · NICHD · PRINCETON UNIVERSITY · PI MASSEY, DOUGLAS S · 2004 to 2013
$7.3M
Scientific and Technical Computing CoreP2CHD047879 · NICHD · PRINCETON UNIVERSITY · PI MASSEY, DOUGLAS S · 2014 to 2018
$2.0M
NICHD NIH HHS P2C HD047879NICHD NIH HHS R24 HD047879NICHD NIH HHS R24HD047879
6 · The paper itself

Abstract

Emergency contraception (EC) prevents pregnancy after unprotected sex or contraceptive failure. Use of EC has increased markedly in countries where a product is available over the counter, yet barriers to availability and use remain. Although effective in clinical trials, it has not yet been possible to show a public health benefit of EC in terms of reduction of unintended pregnancy rates. Selective progesterone receptor modulators developed as emergency contraceptives offer better effectiveness than levonorgestrel, but still EC is less effective than use of ongoing regular contraception. Methods which inhibit ovulation whenever they are taken or which act after ovulation to prevent implantation and strategies to increase the uptake of effective ongoing contraception after EC use would prevent more pregnancies.

Indexed as

AdolescentAdultCoitusContraceptionContraception, PostcoitalContraceptive AgentsContraceptives, PostcoitalFemaleFertilityHumansLevonorgestrelMiddle AgedOvulationPregnancyPregnancy RatePregnancy, UnplannedContraceptive AgentsContraceptives, PostcoitalLevonorgestrelcontraceptioneffectivenessemergencyfuturereview

Identifiers

PMID25678571
PMCPMC4447791

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.