Evidence map›Paper›PMID 25678448›Full record

ArticleCancer2015

Residential racial segregation and mortality among black, white, and Hispanic urban breast cancer patients in Texas, 1995 to 2009.

Sandi L Pruitt, Simon J Craddock Lee, Jasmin A Tiro, Lei Xuan, John M Ruiz, Stephen Inrig

Open access · bronzeAbstract read
In one paragraph

Article in Cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 3 pooled it
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 3 syntheses or guidelines pooled it, 109 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Residential Segregation and Racial Cancer Disparities: A Systematic Review.Journal of racial and ethnic health disparities · 2017
    Pooled it
  4. Examining the Role of the Social Vulnerability Index in the Association between Race/Ethnicity and Breast Cancer Outcomes.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
  5. Article
  6. State-Level Structural Racism and Incident Coronary Heart Disease.Journal of the American Heart Association · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Racialized Economic Segregation, Treatment, and Outcomes in Women with Triple-Negative Breast Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
  11. Review
  12. A Neighborhood-Level Hispanic Paradox: The Interaction among Hispanic Density, Neighborhood Disadvantage, and Survival in Patients with Breast Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
  13. Measuring Spatial Social Polarization in Public Health Research: A Scoping Review of Methods and Applications.Journal of urban health : bulletin of the New York Academy of Medicine · 2025
    Article
  14. Article
  15. Article
  16. Review
  17. The Role of Residential Segregation in Treatment and Outcomes of Ductal Carcinoma In Situ of the Breast.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
  18. Article
  19. Review
  20. Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sandi L PruittDepartment of Clinical Sciences, The University of Texas Southwestern Medical Center, Dallas, Texas.
Simon J Craddock LeeDepartment of Clinical Sciences, The University of Texas Southwestern Medical Center, Dallas, Texas.
Jasmin A TiroDepartment of Clinical Sciences, The University of Texas Southwestern Medical Center, Dallas, Texas.
Lei XuanDepartment of Clinical Sciences, The University of Texas Southwestern Medical Center, Dallas, Texas.
John M RuizDepartment of Psychology, University of North Texas, Denton, Texas.
Stephen InrigDepartment of Clinical Sciences, The University of Texas Southwestern Medical Center, Dallas, Texas.
The University of Texas Southwestern Medical Center · USUniversity of North Texas · US

Funding

UT Southwestern Center for Translational Medicine (UL1/KL2/TL1)UL1TR001105 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2013 to 2017
$24.5M
UT Southwestern Center of Patient-Centered Outcomes Research (PCOR)R24HS022418 · AHRQ · UT SOUTHWESTERN MEDICAL CENTER · PI HALM, ETHAN A · 2013 to 2017
$5.0M
AHRQ HHS R24 HS022418AHRQ HHS R24 HS 22,418-01NCATS NIH HHS UL1 TR001105NIMHD NIH HHS L60 MD003664
6 · The paper itself

Abstract

backgroundThe authors investigated whether residential segregation (the degree to which racial/ethnic groups live separately from one another in a geographic area) 1) was associated with mortality among urban women with breast cancer, 2) explained racial/ethnic disparities in mortality, and 3) whether its association with mortality varied by race/ethnicity.

methodsUsing Texas Cancer Registry data, all-cause mortality and breast-cancer mortality were examined among 109,749 urban black, Hispanic, and white women aged ≥50 years who were diagnosed with breast cancer from 1995 to 2009. Racial (black) segregation and ethnic (Hispanic) segregation of patient's neighborhoods were measured and were compared with the larger metropolitan statistical area using the location quotient measure. Shared frailty Cox proportional hazard models were used to nest patients within residential neighborhoods (census tract) and were controlled for race/ethnicity, age, diagnosis year, tumor stage, grade, histology, neighborhood poverty, and county-level mammography availability.

resultsGreater black segregation and Hispanic segregation were adversely associated with cause-specific mortality and all-cause mortality. For example, in adjusted models, Hispanic segregation was associated with cause-specific mortality (adjusted hazard ratio, 1.24; 95% confidence interval, 1.05-1.46). Compared with whites, blacks had higher mortality for both outcomes, whereas Hispanics demonstrated equivalent (cause-specific) or lower (all-cause) mortality. Segregation did not explain racial/ethnic disparities in mortality. Within each race/ethnicity strata, segregation was either adversely associated with mortality or was not significant.

conclusionsAmong urban women with breast cancer in Texas, segregation has an independent, adverse association with mortality, and the effect of segregation varies by patient race/ethnicity. The novel application of a small-area measure of relative racial segregation should be examined in other cancer types with documented racial/ethnic disparities across varied geographic areas.

Indexed as

AgedBlack or African AmericanBlack PeopleBreast NeoplasmsFemaleHealth Status DisparitiesHispanic or LatinoHumansProportional Hazards ModelsResidence CharacteristicsTexasUrban PopulationWhite Peoplebreast cancerethnicityhealth disparitymortalityracesegregation

Identifiers

PMID25678448
PMCPMC5308210
OpenAlexW1561469389

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.