Evidence map›Paper›PMID 25677994›Full record

ReviewClinics in perinatology2015

Urinary tract infections in the infant.

Mehreen Arshad, Patrick C Seed

Abstract readReview
In one paragraph

Review in Clinics in perinatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 4 pooled it
7.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 4 syntheses or guidelines pooled it, 128 citations in OpenAlex.

  1. Pooled it
  2. Treatment of positive urine cultures in the neonatal intensive care unit: a guideline to reduce antibiotic utilization.Journal of perinatology : official journal of the California Perinatal Association · 2021
    Guideline
  3. Pooled it
  4. Pooled it
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Antibiotics (Basel, Switzerland) · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Association Between Antibiotic Duration and Recurrence of Urinary Tract Infection in the Neonatal Critical Care Unit.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2024
    Article
  14. Article
  15. Effects of deferoxamine on intrinsic colistin resistance ofExperimental and therapeutic medicine · 2023
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mehreen ArshadDivision of Infectious Diseases, Department of Pediatrics, Duke University School of Medicine, DUMC 3499, Durham, NC 27710, USA.
Patrick C SeedDivision of Infectious Diseases, Department of Pediatrics, Duke University School of Medicine, DUMC 3499, Durham, NC 27710, USA. Electronic address: patrick.seed@duke.edu.
Duke University · US

Funding

Pediatric Scientist Development Program (PSDP) [K12]K12HD000850 · NICHD · YALE UNIVERSITY · PI Sallie R. Permar · 1987 to 2026
$44.1M
Center for Molecular &Cellular Studies of Ped DiseaseK12HD043494 · NICHD · DUKE UNIVERSITY · PI REED, ANN M. · 2003 to 2017
$5.2M
NICHD NIH HHS K12 HD000850NICHD NIH HHS K12 HD043494
6 · The paper itself

Abstract

Urinary tract infection (UTI) in an infant may be the first indication of an underlying renal disorder. Early recognition and initiation of adequate therapy for UTI is important to reduce the risk of long-term renal scarring. Ampicillin and gentamicin are traditionally the empiric treatment of choice; however, local antibiotic resistance patterns should be considered. Maternal antibiotics during pregnancy also increase the risk of resistant pathogens during neonatal UTI. Long-term management after the first UTI in infants remains controversial because of lack of specific studies in this age group and the risk-benefit issues for antibiotic prophylaxis between reduced recurrent disease and emergent antibiotic resistance.

Indexed as

Drug Resistance, BacterialAnti-Bacterial AgentsAntibiotic ProphylaxisCandidiasisCircumcision, MaleEscherichia coli InfectionsFemaleHumansInfantInfant, NewbornInfant, PrematureMaleUrinary Tract InfectionsUrogenital AbnormalitiesVesico-Ureteral RefluxAnti-Bacterial AgentsAntibiotic resistanceEscherichia coliInfantsRenal imagingUrinary tract infectionVesicoureteral reflux

Identifiers

PMID25677994
PMCPMC5511626
OpenAlexW2076297971

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.