ArticleStudies in history and philosophy of biological and biomedical sciences2015
Implications of the apportionment of human genetic diversity for the apportionment of human phenotypic diversity.
Article in Studies in history and philosophy of biological and biomedical sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 34 citations in OpenAlex.
- Representation in genetic studies affects inference about genetic architecture.bioRxiv : the preprint server for biology · 2026Article
- Impact of Exon 1 polymorphism in the MBL2 gene on MBL serum levels and infection susceptibility in acute lymphoid leukemia.Scientific reports · 2025Article
- Genes, culture, and scientific racism.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Human population dynamics in Upper Paleolithic Europe inferred from fossil dental phenotypes.Science advances · 2024Article
- Article
- The background and legacy of Lewontin's apportionment of human genetic diversity.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- The apportionment of citations: a scientometric analysis of Lewontin 1972.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Re-situations of scientific knowledge: a case study of a skirmish over clusters vs clines in human population genomics.History and philosophy of the life sciences · 2022Article
- Skin deep: The decoupling of genetic admixture levels from phenotypes that differed between source populations.American journal of physical anthropology · 2021Article
- The Phenotypic Consequences of Genetic Divergence between Admixed Latin American Populations: Antioquia and Chocó, Colombia.Genome biology and evolution · 2020Article
- Testing the utility of dental morphological trait combinations for inferring human neutral genetic variation.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Evolutionary perspectives on polygenic selection, missing heritability, and GWAS.Human genetics · 2020Review
- Interpreting polygenic scores, polygenic adaptation, and human phenotypic differences.Evolution, medicine, and public health · 2019Review
- Linkage disequilibrium matches forensic genetic records to disjoint genomic marker sets.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Recent advances in the study of fine-scale population structure in humans.Current opinion in genetics & development · 2016Review
- Population Genomics and the Statistical Values of Race: An Interdisciplinary Perspective on the Biological Classification of Human Populations and Implications for Clinical Genetic Epidemiological Research.Frontiers in genetics · 2016Review
- A General Model of the Relationship between the Apportionment of Human Genetic Diversity and the Apportionment of Human Phenotypic Diversity.Human biology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Researchers in many fields have considered the meaning of two results about genetic variation for concepts of "race." First, at most genetic loci, apportionments of human genetic diversity find that worldwide populations are genetically similar. Second, when multiple genetic loci are examined, it is possible to distinguish people with ancestry from different geographical regions. These two results raise an important question about human phenotypic diversity: To what extent do populations typically differ on phenotypes determined by multiple genetic loci? It might be expected that such phenotypes follow the pattern of similarity observed at individual loci. Alternatively, because they have a multilocus genetic architecture, they might follow the pattern of greater differentiation suggested by multilocus ancestry inference. To address the question, we extend a well-known classification model of Edwards (2003) by adding a selectively neutral quantitative trait. Using the extended model, we show, in line with previous work in quantitative genetics, that regardless of how many genetic loci influence the trait, one neutral trait is approximately as informative about ancestry as a single genetic locus. The results support the relevance of single-locus genetic-diversity partitioning for predictions about phenotypic diversity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.