ReviewNeuroscience2015
Neurobiological mechanisms supporting experience-dependent resistance to social stress.
Review in Neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 38 citations in OpenAlex.
- What matters to a mouse? Effects of internal and external context on male vocal response to female squeaks.PloS one · 2025Article
- Effects of social dominance and acute social stress on morphology of microglia and structural integrity of the medial prefrontal cortex.Brain, behavior, and immunity · 2024Article
- Prior experience with behavioral control over stress facilitates social dominance.Neurobiology of stress · 2024Article
- Sex and social status modify the effects of fluoxetine on socioemotional behaviors in Syrian hamsters and rhesus macaques.Pharmacology, biochemistry, and behavior · 2022Article
- Defense mechanism responses to COVID-19.PeerJ · 2022Review
- Glutamatergic Neurotransmission Controls the Functional Lateralization of the mPFC in the Modulation of Anxiety Induced by Social Defeat Stress in Male Mice.Frontiers in behavioral neuroscience · 2021Article
- Correlated Neural Activity and Encoding of Behavior across Brains of Socially Interacting Animals.Cell · 2019Article
- Selective activation of parvalbumin interneurons prevents stress-induced synapse loss and perceptual defects.Molecular psychiatry · 2018Article
- Social rank-associated stress vulnerability predisposes individuals to cocaine attraction.Scientific reports · 2018Article
- Dominance status alters restraint-induced neural activity in brain regions controlling stress vulnerability.Physiology & behavior · 2017Article
- Cortical adrenoceptor expression, function and adaptation under conditions of cannabinoid receptor deletion.Experimental neurology · 2017Article
- Stress, sex, and motivated behaviors.Journal of neuroscience research · 2017Review
- Sex Differences in the Regulation of Offensive Aggression and Dominance by Arginine-Vasopressin.Frontiers in endocrinology · 2017Review
- Sex differences in the effects of social defeat on brain and behavior in the California mouse: Insights from a monogamous rodent.Seminars in cell & developmental biology · 2017Review
- Serotonin and arginine-vasopressin mediate sex differences in the regulation of dominance and aggression by the social brain.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Winning agonistic encounters increases testosterone and androgen receptor expression in Syrian hamsters.Hormones and behavior · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Humans and other animals show a remarkable capacity for resilience following traumatic, stressful events. Resilience is thought to be an active process related to coping with stress, although the cellular and molecular mechanisms that support active coping and stress resistance remain poorly understood. In this review, we focus on the neurobiological mechanisms by which environmental and social experiences promote stress resistance. In male Syrian hamsters, exposure to a brief social defeat stressor leads to increased avoidance of novel opponents, which we call conditioned defeat. Also, hamsters that have achieved dominant social status show reduced conditioned defeat as well as cellular and molecular changes in the neural circuits controlling the conditioned defeat response. We propose that experience-dependent neural plasticity occurs in the prelimbic (PL) cortex, infralimbic (IL) cortex, and ventral medial amygdala (vMeA) during the maintenance of dominance relationships, and that adaptations in these neural circuits support stress resistance in dominant individuals. Overall, behavioral treatments that promote success in competitive interactions may represent valuable interventions for instilling resilience.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.