ArticleJournal of biophotonics2015
Handheld photoacoustic probe to detect both melanoma depth and volume at high speed in vivo.
Article in Journal of biophotonics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Photoacoustic imaging for cutaneous melanoma assessment: a comprehensive review.Journal of biomedical optics · 2024Pooled it
- Review of Non-Invasive Imaging Technologies for Cutaneous Melanoma.Biosensors · 2025Review
- Combined ultrasound and photoacoustic C-mode imaging system for skin lesion assessment.Scientific reports · 2023Article
- Efficient label-freePhotoacoustics · 2023Article
- Early diagnosis of bladder cancer by photoacoustic imaging of tumor-targeted gold nanorods.Photoacoustics · 2022Article
- Long-Duration and Non-Invasive Photoacoustic Imaging of Multiple Anatomical Structures in a Live Mouse Using a Single Contrast Agent.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Theranostics Using Indocyanine Green Lactosomes.Cancers · 2022Review
- Seeing through the Skin: Photoacoustic Tomography of Skin Vasculature and Beyond.JID innovations : skin science from molecules to population health · 2021Review
- Comparison of photoacoustic imaging and histopathological examination in determining the dimensions of 52 human melanomas and neviBiomedical optics express · 2021Article
- Transrectal Ultrasound and Photoacoustic Imaging Probe for Diagnosis of Prostate Cancer.Sensors (Basel, Switzerland) · 2021Article
- Towards non-contact photoacoustic imaging [review].Photoacoustics · 2020Review
- Improved Depth-of-Field Photoacoustic Microscopy with a Multifocal Point Transducer for Biomedical Imaging.Sensors (Basel, Switzerland) · 2020Article
- Photoacoustic image-guided interventions.Experimental biology and medicine (Maywood, N.J.) · 2020Review
- Listening to tissues with new light: recent technological advances in photoacoustic imaging.Journal of optics (2010) · 2019Article
- Photoacoustic/Ultrasound/Optical Coherence Tomography Evaluation of Melanoma Lesion and Healthy Skin in a Swine Model.Sensors (Basel, Switzerland) · 2019Article
- A Handheld Real-Time Photoacoustic Imaging System for Animal Neurological Disease Models: From Simulation to Realization.Sensors (Basel, Switzerland) · 2018Article
- Hand-held optoacoustic imaging: A review.Photoacoustics · 2018Review
- Linear array-based real-time photoacoustic imaging system with a compact coaxial excitation handheld probe for noninvasive sentinel lymph node mapping.Biomedical optics express · 2018Article
- Bioinspired Multifunctional Melanin-Based Nanoliposome for Photoacoustic/Magnetic Resonance Imaging-Guided Efficient Photothermal Ablation of Cancer.Theranostics · 2018Article
- Preoperative measurement of cutaneous melanoma and nevi thickness with photoacoustic imaging.Journal of medical imaging (Bellingham, Wash.) · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
We applied a linear-array-based photoacoustic probe to detect melanin-containing melanoma tumor depth and volume in nude mice in vivo. This system can image melanomas at five frames per second (fps), which is much faster than our previous handheld single transducer system (0.1 fps). We first theoretically show that, in addition to the higher frame rate, almost the entire boundary of the melanoma can be detected by the linear-array-based probe, while only the horizontal boundary could be detected by the previous system. Then we demonstrate the ability of this linear-array-based system in measuring both the depth and volume of melanoma through phantom, ex vivo, and in vivo experiments. The volume detection ability also enables us to accurately calculate the rate of growth of the tumor, which is an important parameter in quantifying the tumor activity. Our results show that this system can be used for clinical melanoma diagnosis and treatment in humans at the bedside. Linear-array-based PA images of melanoma acquired in vivo on day 3 (a) and day 6 (b).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.