Evidence map›Paper›PMID 25676384›Full record

ArticleCephalalgia : an international journal of headache2015

Headache neuroimaging: Routine testing when guidelines recommend against them.

Brian C Callaghan, Kevin A Kerber, Robert J Pace, Lesli Skolarus, Wade Cooper, James F Burke

Abstract read
In one paragraph

Article in Cephalalgia : an international journal of headache, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 50 citations in OpenAlex.

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  19. Portable Ultra-Low-Field MRI in Outpatient Neurology: An Examination of Clinical Performance and Patient Experience.Journal of neuroimaging : official journal of the American Society of Neuroimaging
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Brian C CallaghanUniversity of Michigan, Ann Arbor, USA bcallagh@med.umich.edu.
Kevin A KerberUniversity of Michigan, Ann Arbor, USA.
Robert J PaceUniversity of Michigan, Ann Arbor, USA.
Lesli SkolarusUniversity of Michigan, Ann Arbor, USA.
Wade CooperUniversity of Michigan, Ann Arbor, USA.
James F BurkeUniversity of Michigan, Ann Arbor, USA VA Center for Clinical Management Research, USA.
University of Michigan–Ann Arbor · USVA Center for Clinical Management Research · US

Funding

Implementation of Evidence-Based Practice for Benign Paroxysmal Positional VertigR01DC012760 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KERBER, KEVIN ANTHONY, MEURER, WILLIAM JOSEPH · 2013 to 2024
$6.2M
Solutions for Vertigo presentations in the Emergency Department (SOLVE) ProjectR18HS017690 · AHRQ · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KERBER, KEVIN ANTHONY · 2009 to 2012
$1.5M
Using Outcomes Analyses to Inform Implementation of NINDS Clinical TrialsK08NS082597 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BURKE, JAMES FRANCIS · 2013 to 2017
$948k
The Impact of the Metabolic Syndrome on NeuropathyK23NS079417 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CALLAGHAN, BRIAN CHRISTOPHER · 2013 to 2017
$939k
A Community Partnership to Treat StrokeK23NS073685 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SKOLARUS, LESLI ELIZABETH · 2011 to 2016
$924k
Dizziness in the Emergency Department: A Population-Based ProjectK23RR024009 · NCRR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KERBER, KEVIN ANTHONY · 2007 to 2011
$797k
A stroke preparedness assessment instrumentR21NS084081 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MORGENSTERN, LEWIS B, SKOLARUS, LESLI ELIZABETH · 2014 to 2015
$446k
AHRQ HHS R18 HS017690NCRR NIH HHS K23 RR024009NIDCD NIH HHS 1R01DC012760NIDCD NIH HHS R01 DC012760NINDS NIH HHS K08 NS082597NINDS NIH HHS K23 NS073685NINDS NIH HHS K23NS073685NINDS NIH HHS K23 NS079417NINDS NIH HHS R21 NS084081NINDS NIH HHS R21-NS-084081
6 · The paper itself

Abstract

aimsThe aim of this article is to determine the patient-level factors associated with headache neuroimaging in outpatient practice.

methodsUsing data from the 2007-2010 National Ambulatory Medical Care Surveys (NAMCS), we estimated headache neuroimaging utilization (cross-sectional). Multivariable logistic regression was used to explore associations between patient-level factors and neuroimaging utilization. A Markov model with Monte Carlo simulation was used to estimate neuroimaging utilization over time at the individual patient level.

resultsMigraine diagnoses (OR = 0.6, 95% CI 0.4-0.9) and chronic headaches (routine, chronic OR = 0.3, 95% CI 0.2-0.6; flare-up, chronic OR = 0.5, 95% CI 0.3-0.96) were associated with lower utilization, but even in these populations neuroimaging was ordered frequently. Red flags for intracranial pathology did not increase use of neuroimaging studies (OR = 1.4, 95% CI 0.95-2.2). Neurologist visits (OR = 1.7, 95% CI 0.99-2.9) and first visits to a practice (OR = 3.2, 95% CI 1.4-7.4) were associated with increased imaging. A patient with new migraine headaches has a 39% (95% CI 24-54%) chance of receiving a neuroimaging study after five years and a patient with a flare-up of chronic headaches has a 51% (32-68%) chance.

conclusionsNeuroimaging is routinely ordered in outpatient headache patients including populations where guidelines specifically recommend against their use (migraines, chronic headaches, no red flags).

Indexed as

AdolescentAdultAgedCross-Sectional StudiesFemaleHeadacheHealth Care SurveysHumansMaleMiddle AgedMonte Carlo MethodNeuroimagingPractice Guidelines as TopicYoung Adultdiagnostic testingHeadacheshealth care efficienciesmigraines

Identifiers

PMID25676384
PMCPMC5522585
OpenAlexW2332474150

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.