Evidence map›Paper›PMID 25676333›Full record

ArticleScientific reports2015

Study of DNA adsorption on mica surfaces using a surface force apparatus.

Yajing Kan, Qiyan Tan, Gensheng Wu, Wei Si, Yunfei Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. CoNanoscale · 2025
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  8. Review
  9. Constructing Large 2D Lattices Out of DNA-Tiles.Molecules (Basel, Switzerland) · 2021
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yajing KanJiangsu Key Laboratory for Design and Manufacture of Micro-Nano Biomedical Instruments, and School of Mechanical Engineering, Southeast University, Nanjing 211189, China.
Qiyan TanJiangsu Key Laboratory for Design and Manufacture of Micro-Nano Biomedical Instruments, and School of Mechanical Engineering, Southeast University, Nanjing 211189, China.
Gensheng WuJiangsu Key Laboratory for Design and Manufacture of Micro-Nano Biomedical Instruments, and School of Mechanical Engineering, Southeast University, Nanjing 211189, China.
Wei SiJiangsu Key Laboratory for Design and Manufacture of Micro-Nano Biomedical Instruments, and School of Mechanical Engineering, Southeast University, Nanjing 211189, China.
Yunfei ChenJiangsu Key Laboratory for Design and Manufacture of Micro-Nano Biomedical Instruments, and School of Mechanical Engineering, Southeast University, Nanjing 211189, China.
Southeast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report our studies on the adsorption properties of double-stranded DNA molecules on mica surfaces in a confined environment using a surface force apparatus. Specifically, we studied the influence of cation species and concentrations on DNA adsorption properties. Our results indicated that divalent cations (Mg(2+) and Co(2+)) preferred to form uniform and moderately dense DNA layers on a mica substrate. By measuring the interactions between DNA-coated mica and bare mica in an aqueous solution, obvious adhesion was observed in a cobalt chloride solution, possibly due to the ion-correlation attraction between negatively charged DNA and the mica surface. Furthermore, the interaction differences that were observed with MgCl2 and CoCl2 solutions reveal that the specific adsorption behaviors of DNA molecules on a mica substrate were mediated by these two salts. Our results are helpful to elucidate the dynamics of DNA binding on a solid substrate.

Indexed as

AdsorptionAluminum SilicatesCationsCobaltDNAMagnesium ChlorideSurface PropertiesAluminum SilicatesCationsCobaltcobaltous chlorideDNAMagnesium Chloridemica

Identifiers

PMID25676333
PMCPMC4326959
OpenAlexW2029287468

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.