Evidence map›Paper›PMID 25676118›Full record

ReviewMedizinische Klinik, Intensivmedizin und Notfallmedizin2015

[Lung and kidney failure. Pathogenesis, interactions, and therapy].

S John, C Willam

Abstract readReview
PubMed Publisher
In one paragraph

Review in Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Organ crosstalk: the potent roles of inflammation and fibrotic changes in the course of organ interactions.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2019
    Review
  4. Low-flow COAnnals of intensive care · 2019
    Article
  5. Cyclic PaOBMC anesthesiology · 2017
    Article
  6. [Hypoxic respiratory failure in chronic lung disease].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2017
    Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

S JohnMedizinische Klinik 4, Universität Erlangen-Nürnberg, Erlangen, Deutschland. stefan.john@uk-erlangen.de.
C WillamMedizinische Klinik 4, Universität Erlangen-Nürnberg, Erlangen, Deutschland.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe lungs and kidneys represent the most often affected organs (acute respiratory distress syndrome, ARDS or kidney failure) in multiple organ failure (MOF) due to shock, trauma, or sepsis with a still unacceptable high mortality for both organ failures. PATHOGENESIS AND INTERACTIONS: Although the exact pathophysiological mechanisms of MOF are not completely elucidated, it appears that the lungs and kidneys share several pathophysiologic pathways and have the potential to further harm each other (kidney-lung crosstalk). Inflammatory signals in both directions and volume overload with consecutive edema formation in both organs may play a key role in this crosstalk. TREATMENT: The organ replacement therapies used in both organ failures have the potential to further injure the other organ (ventilator trauma, dialyte trauma). On the other hand, renal replacement therapy can have positive effects on lung injury by restoring volume and acid-base homeostasis. The new development of "low-flow" extracorporeal CO2 removal on renal replacement therapy platforms may further help to decrease ventilator trauma in the future.

Indexed as

Critical CareExtracorporeal Membrane OxygenationFluid TherapyHumansKidneyLungMultiple Organ FailureRenal InsufficiencyRenal Replacement TherapyRespiration, ArtificialRespiratory Distress SyndromeSepsisSurvival AnalysisAcute kidney injuryARDS, humanExtracorporeal CO2-eliminationMechanical ventilationRenal replacement therapy

Identifiers

PMID25676118
OpenAlexW165958332

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.