Evidence map›Paper›PMID 25675000›Full record

ArticleMarine drugs2015

New Insights on the terpenome of the red seaweed Laurencia dendroidea (Florideophyceae, Rhodophyta).

Louisi Souza de Oliveira, Diogo Antonio Tschoeke, Aline Santos de Oliveira, Lilian Jorge Hill, Wladimir Costa Paradas, Leonardo Tavares Salgado, Cristiane Carneiro Thompson, Renato Crespo Pereira, Fabiano L Thompson

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 50 citations in OpenAlex.

  1. Laurinterol, the MainMarine drugs · 2026
    Review
  2. Marine drugs · 2026
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  3. Marine drugs · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Louisi Souza de OliveiraInstitute of Biology, Federal University of Rio de Janeiro (UFRJ) Av. Carlos Chagas Filho, 373-CCS-IB-BLOCO A (ANEXO) A3-202, SAGE-COPPE, Rio de Janeiro 21941-599, Brazil. louisioliveira@gmail.com.
Diogo Antonio TschoekeInstitute of Biology, Federal University of Rio de Janeiro (UFRJ) Av. Carlos Chagas Filho, 373-CCS-IB-BLOCO A (ANEXO) A3-202, SAGE-COPPE, Rio de Janeiro 21941-599, Brazil. diogoat@gmail.com.
Aline Santos de OliveiraFederal Institute of Education, Science and Technology of Rio de Janeiro (IFRJ), Campus Duque de Caxias, Avenida República do Paraguai, 120, Sarapuí, Duque de Caxias 25050-100, Brazil. linesoliveira@gmail.com.
Lilian Jorge HillResearch Institute of the Botanical Garden of Rio de Janeiro, Rua Pacheco Leão, 915, Jardim Botânico, Rio de Janeiro 22460-030, Brazil. lilianhill.bio@gmail.com.
Wladimir Costa ParadasResearch Institute of the Botanical Garden of Rio de Janeiro, Rua Pacheco Leão, 915, Jardim Botânico, Rio de Janeiro 22460-030, Brazil. wladimirparadas@gmail.com.
Leonardo Tavares SalgadoResearch Institute of the Botanical Garden of Rio de Janeiro, Rua Pacheco Leão, 915, Jardim Botânico, Rio de Janeiro 22460-030, Brazil. lsalgado.jbrj@gmail.com.
Cristiane Carneiro ThompsonInstitute of Biology, Federal University of Rio de Janeiro (UFRJ) Av. Carlos Chagas Filho, 373-CCS-IB-BLOCO A (ANEXO) A3-202, SAGE-COPPE, Rio de Janeiro 21941-599, Brazil. thompsoncristiane@gmail.com.
Renato Crespo PereiraDepartament of Marine Biology, Federal Fluminense University (UFF), Morro do Valonguinho, s/n, Centro, Niterói 24001-970, Brazil. rcrespo@id.uff.br.
Fabiano L ThompsonInstitute of Biology, Federal University of Rio de Janeiro (UFRJ) Av. Carlos Chagas Filho, 373-CCS-IB-BLOCO A (ANEXO) A3-202, SAGE-COPPE, Rio de Janeiro 21941-599, Brazil. fabianothompson1@gmail.com.
Universidade Federal do Rio de Janeiro · BRInstituto de Pesquisas Jardim Botânico do Rio de Janeiro · BRRio de Janeiro Federal Institute of Education, Science and Technology · BRUniversidade Federal Fluminense · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The red seaweeds belonging to the genus Laurencia are well known as halogenated secondary metabolites producers, mainly terpenoids and acetogennins. Several of these chemicals exhibit important ecological roles and biotechnological applications. However, knowledge regarding the genes involved in the biosynthesis of these compounds is still very limited. We detected 20 different genes involved in the biosynthesis of terpenoid precursors, and 21 different genes coding for terpene synthases that are responsible for the chemical modifications of the terpenoid precursors, resulting in a high diversity of carbon chemical skeletons. In addition, we demonstrate through molecular and cytochemical approaches the occurrence of the mevalonate pathway involved in the biosynthesis of terpenes in L. dendroidea. This is the first report on terpene synthase genes in seaweeds, enabling further studies on possible heterologous biosynthesis of terpenes from L. dendroidea exhibiting ecological or biotechnological interest.

Indexed as

Alkyl and Aryl TransferasesBiosynthetic PathwaysCarbohydrate ConformationDNA, ComplementaryLaurenciaMevalonic AcidModels, MolecularTerpenesTranscriptomeAlkyl and Aryl TransferasesDNA, ComplementaryMevalonic AcidTerpenesterpene synthase

Identifiers

PMID25675000
PMCPMC4344607
OpenAlexW2039737174

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.