ArticleMedicine2015
Clinicoradiological spectrum of reversible splenial lesion syndrome (RESLES) in adults: a retrospective study of a rare entity.
Article in Medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Article
- Reversible splenial lesion syndrome associated with Graves' disease and hepatic dysfunction: a case report.Frontiers in neuroscience · 2025Article
- Altitude-related features and prognosis in patients with reversible splenial lesion syndrome.Annals of medicine · 2024Article
- Mild encephalitis/encephalopathy with reversible splenial lesion (MERS) associated with respiratory syncytial virus andHeliyon · 2024Article
- Article
- Hemorrhagic fever with renal syndrome and reversible splenial lesion syndrome.Neurosciences (Riyadh, Saudi Arabia) · 2023Article
- A Rare Case of Reversible Splenial Lesion Syndrome with Extracallosal Lesions in the Setting of Deep Anemia.Asian journal of neurosurgery · 2023Article
- Reversible splenial lesion after surgery for distant arteriovenous malformation: a case report.Acta neurochirurgica · 2023Article
- An elderly man with mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) without neuropsychiatric sequelae.Clinical case reports · 2023Article
- Case report: Clinically mild encephalitis/encephalopathy with a reversible splenial lesion: an autopsy case.Frontiers in neurology · 2023Article
- Mild Encephalitis/Encephalopathy with a Reversible Lesion in The Splenium.Noro psikiyatri arsivi · 2023Article
- Reversible Splenial Lesion Syndrome as a Challenging Casuistry.International journal of environmental research and public health · 2022Article
- Article
- Severe Dengue with Rapid Onset Dementia, Apraxia of Speech and Reversible Splenial Lesion.Journal of neurosciences in rural practice · 2021Article
- Reversible splenial lesion syndrome in sisters with sensorineural deafness as the first manifestation.Heliyon · 2021Article
- Clinically Mild Encephalopathy with a Reversible Splenial Lesion Caused by Influenza B Virus in an Unvaccinated Child.Pediatric reports · 2021Article
- Vertigo and Cytotoxic Lesions of the Corpus Callosum: Report with Review of the Literature.Case reports in neurological medicine · 2021Article
- Clinically mild encephalitis/encephalopathy with reversible splenial lesion (MERS) associated withClinical case reports · 2020Article
- Reversible Splenial Lesion Syndrome with Some Novel Causes and Clinical Manifestations.Internal medicine (Tokyo, Japan) · 2020Observational
- Clinical analysis of reversible splenial lesion syndrome in Chinese adults: A retrospective study of 11 cases.Medicine · 2020Article
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3 authors.
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Abstract
The presence of reversible lesions that involve the splenium of the corpus callosum (SCC) has been reported in patients with a broad spectrum of diseases and conditions and is referred to as reversible splenial lesion syndrome (RESLES).To describe the clinicoradiological features and establish a clinical position for this disease, we retrospectively examined the clinicoradiological features of adult RESLES patients, as well as discuss the potential pathophysiological mechanisms of this disease.The clinical and MRI findings of patients who presented with RESLES accompanied by symptoms of neurological disorders were retrospectively reviewed. The patients were classified into 2 subgroups (favorable and poor outcome subgroups), which corresponded to the severity of the disability using the Modified Oxford Handicap Scale. In addition, we compared the clinical and neuroimaging features between the 2 outcome subgroups.Eight patients with RESLES associated with various diseases and conditions were included. The clinical presentation was nonspecific; however, MRI exhibited consistent lesions in the SCC with a hypointensity on apparent diffusion coefficient maps and a hyperintensity via diffusion-weighted imaging, which disappeared after a variable lapse. The number of patients with a severe disturbance of consciousness, extracallosal lesions, or diffuse slow waves in the poor outcome subgroup was significantly increased compared with the favorable outcome subgroup (P < 0.05). Thus, the clinicoradiological spectrum of RESLES could be classified into 2 principal categories according to differential outcomes.RESLES is a rare entity with a broad clinicoradiological spectrum because of the various diseases and conditions. Although the overall symptoms of RESLES patients tend to be alleviated, the prognosis of patients with a severe disturbance of consciousness, extracallosal lesions, or diffuse slow waves is likely unfavorable.
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